Evidence map›Paper›PMID 31078338›Full record

ArticleThe Journal of hand surgery2019

Frequency and Risk Factors for Prolonged Opioid Prescriptions After Surgery for Brachial Plexus Injury.

Christopher J Dy, Kate Peacock, Margaret A Olsen, Wilson Z Ray, David M Brogan

Open access · greenAbstract read
In one paragraph

Article in The Journal of hand surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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  10. What's New in Hand and Wrist Surgery.The Journal of bone and joint surgery. American volume · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christopher J DyDepartment of Orthopaedic Surgery, Division of Hand and Microsurgery, Washington University School of Medicine, St. Louis, MO; Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO. Electronic address: dyc@wustl.edu.
Kate PeacockDepartment of Medicine, Center for Administrative Data Research, Washington University School of Medicine, St. Louis, MO.
Margaret A OlsenDepartment of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO; Department of Medicine, Center for Administrative Data Research, Washington University School of Medicine, St. Louis, MO.
Wilson Z RayDepartment of Neurological Surgery, Washington University School of Medicine, St. Louis, MO.
David M BroganDepartment of Orthopaedic Surgery, Division of Hand and Microsurgery, Washington University School of Medicine, St. Louis, MO.
Washington University in St. Louis · USNeurological Surgery · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
WASHINGTON UNIVERSITY CER MENTORED CAREER DEVELOPMENT AWARD KM1KM1CA156708 · NCI · WASHINGTON UNIVERSITY · PI FRASER, VICTORIA J. · 2010 to 2010
$2.5M
Understanding Barriers to Delivery of Care for Patients with Adult Traumatic Brachial Plexus InjuryK23AR073928 · NIAMS · WASHINGTON UNIVERSITY · PI DY, CHRISTOPHER JOHN · 2018 to 2020
$465k
AHRQ HHS R24 HS019455NCATS NIH HHS KL2 TR000450NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS KM1 CA156708NIAMS NIH HHS K23 AR073928NIAMS NIH HHS L30 AR075547
6 · The paper itself

Abstract

purposeWe hypothesized that patients with preoperative opioid prescriptions and diagnoses of depression and anxiety would be at increased risk for prolonged opioid prescriptions after surgery for brachial plexus injury (BPI).

methodsUsing an administrative database of privately insured patients, we assembled a cohort of BPI surgery patients and a control group of non-BPI patients, matching for age, sex, and year. Pharmacy claims for prescriptions filled for opioids and neuropathic pain medications were examined 12 months before surgery to 180 days after surgery. The primary outcome was prolonged opioid prescription, defined as receiving a prescription 90 to 180 days after the index (BPI surgery or randomly selected date of service for controls). Multivariable regression was used to examine risk factors for postoperative opioid use, including diagnoses of depression, anxiety, drug abuse, tobacco use, and preoperative use of opioids and neuropathic pain medications. A subgroup analysis was performed for opioid-naive BPI patients between 30 days to 1 year before surgery.

resultsAmong BPI surgery patients (n = 1,936), 27.7% had prolonged opioid prescriptions. Among opioid-naive BPI patients (n = 911), 10.8% had prolonged opioid prescriptions. In controls (n = 19,360), frequency of prolonged opioid prescriptions was 0.11%. Among all BPI patients, after adjustment for age and sex, predictors of prolonged postoperative opioid prescriptions in BPI patients were preoperative opioids, preoperative neuropathic pain medication use, histories of drug abuse, tobacco use, and anxiety.

conclusionsProlonged postoperative opioids prescriptions after BPI reconstruction are higher than previous estimates among other surgical patients. In addition to establishing normative data among this population, our findings serve to increase awareness of risk factors for prolonged opioids after BPI reconstruction and encourage coordinated multidisciplinary care. TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic II.

Indexed as

AdolescentAdultAnalgesics, OpioidAnxietyBrachial PlexusDepressionFemaleHumansMaleMiddle AgedOpioid-Related DisordersPostoperative PainPractice Patterns, Physicians'Risk FactorsAnalgesics, OpioidBrachial plexuschronic painnerve injuryneuropathic painopioids

Identifiers

PMID31078338
PMCPMC7193763
OpenAlexW2943852816

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.