Evidence map›Paper›PMID 31078209›Full record

ReviewClinics in chest medicine2019

Update on Chemoreception: Influence on Cardiorespiratory Regulation and Pathophysiology.

Jerome A Dempsey, Curtis A Smith

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinics in chest medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Gefapixant as a P2X3 receptor antagonist treatment for obstructive sleep apnea: a randomized controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Trial
  2. Amelioration of sleep-disordered breathing with supplemental oxygen in older adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2020
    Trial
  3. Article
  4. Review
  5. Chemoreceptor mechanisms regulating COThe Journal of physiology · 2021
    Review
  6. Sensory signals mediating high blood pressure via sympathetic activation: role of adipose afferent reflex.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Review
  7. Article
  8. Pulmonology approach in the investigation of chronic unexplained dyspnea.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jerome A DempseyDepartment Population Health Sciences, University of Wisconsin-Madison, 707 WARF Building, 610 N. Walnut Street, WI 53726, USA. Electronic address: jdempsey@wisc.edu.
Curtis A SmithDepartment Population Health Sciences, University of Wisconsin-Madison, 707 WARF Building, 610 N. Walnut Street, WI 53726, USA.
University of Wisconsin–Madison · US

Funding

HUMAN VENTILATORY ADAPTIONR01HL015469 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI DEMPSEY, JEROME A · 1985 to 2011
$3.7M
Use of a Variable Dead Space Rebreathe Device (Smart CO2) to Treat Obstructive and Central Sleep ApneaR21HL137874 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI DEMPSEY, JEROME A · 2017 to 2018
$421k
NHLBI NIH HHS R01 HL015469NHLBI NIH HHS R21 HL137874
6 · The paper itself

Abstract

We examine recent findings that have revealed interdependence of function within the chemoreceptor pathway regulating breathing and sympathetic vasomotor activity and the hypersensitization of these reflexes in chronic disease states. Recommendations are made as to how these states of hyperreflexia in chemoreceptors and muscle afferents might be modified in treating sleep apnea, drug-resistant hypertension, chronic heart failure-induced sympathoexcitation, and the exertional dyspnea of chronic obstructive pulmonary disease.

Indexed as

Cardiorespiratory FitnessChemoreceptor CellsHumansSleep Apnea SyndromesCarotid-medullary chemoreceptor interdependenceHypersensitization of chemoreceptionSensory hyperreflexia in chronic diseases

Identifiers

PMID31078209
PMCPMC6512837
OpenAlexW2944495495

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.