Evidence map›Paper›PMID 31077686›Full record

ArticleThe Journal of allergy and clinical immunology2019

β-Arrestin2 expressed in mast cells regulates ciprofloxacin-induced pseudoallergy and IgE-mediated anaphylaxis.

Saptarshi Roy, Kshitij Gupta, Anirban Ganguly, Hydar Ali

Abstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saptarshi RoyDepartment of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Kshitij GuptaDepartment of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Anirban GangulyDepartment of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa.
Hydar AliDepartment of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pa. Electronic address: alih@upenn.edu.

Funding

Role of a novel human mast cell G protein coupled receptor in Allergy and InflammationR01AI124182 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Hydar Ali · 2016 to 2026
$2.5M
Role of beta-arrestin-2 on IgE-mediated cofilin dephosphorylation and mast cell activationR21AI115688 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ALI, HYDAR · 2015 to 2016
$440k
NIAID NIH HHS R01 AI124182NIAID NIH HHS R21 AI115688
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnaphylaxisAnimalsbeta-Arrestin 2CiprofloxacinDrug HypersensitivityGene Expression RegulationImmunoglobulin EMast CellsMiceMice, KnockoutArrb2 protein, mousebeta-Arrestin 2CiprofloxacinImmunoglobulin E

Identifiers

PMID31077686
PMCPMC6688937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.