Evidence map›Paper›PMID 31077628›Full record

ReviewPlant biotechnology journal2019

MdMYB46 could enhance salt and osmotic stress tolerance in apple by directly activating stress-responsive signals.

Keqin Chen, Mengru Song, Yunna Guo, Lifu Liu, Hao Xue, Hongyan Dai, Zhihong Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Plant biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 228 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Overexpression ofInternational journal of molecular sciences · 2025
    Article
  5. Review
  6. Plants (Basel, Switzerland) · 2025
    Article
  7. Overexpression of aInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Evaluation of Salt Resistance of Six Apple Rootstocks.International journal of molecular sciences · 2024
    Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Keqin ChenGroup of Molecular Biology of Fruit Trees, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Mengru SongGroup of Fruit Germplasm Evaluation & Utilization, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Yunna GuoGroup of Fruit Germplasm Evaluation & Utilization, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Lifu LiuGroup of Fruit Germplasm Evaluation & Utilization, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Hao XueGroup of Molecular Biology of Fruit Trees, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Hongyan DaiGroup of Fruit Germplasm Evaluation & Utilization, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Zhihong ZhangGroup of Molecular Biology of Fruit Trees, College of Horticulture, Shenyang Agricultural University, Shenyang, Liaoning, China.
Shenyang Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To expand the cultivation area of apple (Malus×domestica Borkh.) and select resistant varieties by genetic engineering, it is necessary to clarify the mechanism of salt and osmotic stress tolerance in apple. The MdMYB46 transcription factor was identified, and the stress treatment test of MdMYB46-overexpressing and MdMYB46-RNAi apple lines indicated that MdMYB46 could enhance the salt and osmotic stress tolerance in apple. In transgenic Arabidopsis and apple, MdMYB46 promoted the biosynthesis of secondary cell wall and deposition of lignin by directly binding to the promoter of lignin biosynthesis-related genes. To explore whether MdMYB46 could coordinate stress signal transduction pathways to cooperate with the formation of secondary walls to enhance the stress tolerance of plants, MdABRE1A, MdDREB2A and dehydration-responsive genes MdRD22 and MdRD29A were screened out for their positive correlation with osmotic stress, salt stress and the transcriptional level of MdMYB46. The further verification test demonstrated that MdMYB46 could activate their transcription by directly binding to the promoters of these genes. The above results indicate that MdMYB46 could enhance the salt and osmotic stress tolerance in apple not only by activating secondary cell wall biosynthesis pathways, but also by directly activating stress-responsive signals.

Indexed as

Osmotic PressureStress, PhysiologicalArabidopsisArabidopsis ProteinsGene Expression Regulation, PlantMalusPlant ProteinsPlants, Genetically ModifiedSalt-Tolerant PlantsTranscription FactorsArabidopsis ProteinsMyb46 protein, ArabidopsisPlant ProteinsTranscription FactorsappleMdMYB46osmotic stresssalt stressstress signalling transcription factors

Identifiers

PMID31077628
PMCPMC6835124
OpenAlexW2943968373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.