Evidence map›Paper›PMID 31077523›Full record

ReviewBJU international2019

Management of advanced prostate cancer in a middle-income country: real-world consideration of the Advanced Prostate Cancer Consensus Conference 2017.

Marniza Saad, Adlinda Alip, Jasmine Lim, Matin Mellor Abdullah, Flora Li Tze Chong, Chong Beng Chua, Fuad Ismail, Rachael Kit-Tsan Khong, Chun Sen Lim, Chit Sin Loh and 13 more

Open access · hybridAbstract readReview
In one paragraph

Review in BJU international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 2 countries.

Marniza SaadDepartment of Clinical Oncology, University of Malaya Medical Centre, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Adlinda AlipDepartment of Clinical Oncology, University of Malaya Medical Centre, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Jasmine LimDepartment of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-7501-1834
Matin Mellor AbdullahSubang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia.
Flora Li Tze ChongDepartment of Radiotherapy and Oncology, Sabah Women and Children Hospital, Kota Kinabalu, Sabah, Malaysia.
Chong Beng ChuaGleneagles Intan Medical Centre, Kuala Lumpur, Malaysia.
Fuad IsmailDepartment of Oncology and Radiotherapy, National University of Malaysia, Kuala Lumpur, Malaysia.
Rachael Kit-Tsan KhongGleneagles Intan Medical Centre, Kuala Lumpur, Malaysia.
Chun Sen LimDepartment of Oncology and Radiotherapy, Sultan Ismail Hospital, Johor Bahru, Malaysia.
Chit Sin LohGleneagles Intan Medical Centre, Kuala Lumpur, Malaysia.
Rohan MalekDepartment of Urology, Selayang Hospital, Selangor, Malaysia.
Khairul Asri Mohd GhaniDepartment of Surgery, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia.
Ibtisam Md NoorDepartment of Oncology and Radiotherapy, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.
Noor Ashani Md YusoffDepartment of Urology, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.
Noor Azam NasuhaDepartment of Surgery, Raja Perempuan Zainab II Hospital, Kota Bharu, Kelantan, Malaysia.
Azad RazackDepartment of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Hwoei Fen Soo HooDepartment of Oncology and Radiotherapy, Penang Hospital, Penang, Malaysia.
Murali SundramDepartment of Urology, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.
Hui Meng TanSubang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia.
Muthukkumaran ThiagarajanDepartment of Oncology and Radiotherapy, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia.
Guan Chou TehDepartment of Urology, Sarawak General Hospital, Sarawak, Malaysia.
Pei Jye VoonDepartment of Radiotherapy, Oncology & Palliative Care, Sarawak General Hospital, Sarawak, Malaysia.
Teng Aik OngDepartment of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Hospital Kuala Lumpur · MYGleneagles Hospital · SGUniversity of Malaya · MYSarawak General Hospital · MYSubang Jaya Medical Centre · MYUniversity Malaya Medical Centre · MYHospital Raja Perempuan Zainab II · MYHospital Selayang · MYNational Cancer Council Malaysia · MYRCSI & UCD Malaysia Campus · MYSabah Environmental Trust · MYSultan Ismail Specialist Hospital · MYUniversiti Putra Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the results of the Malaysian Advanced Prostate Cancer Consensus Conference (MyAPCCC) 2018, held for assessing the generalizability of consensus reached at the Advanced Prostate Cancer Consensus Conference (APCCC 2017) to Malaysia, a middle-income country.

methodsSix key sections were chosen: (1) high-risk localized and locally advanced prostate cancer, (2) oligometastatic prostate cancer, (3) castration-naïve prostate cancer, (4) castrate resistant prostate cancer, (5) use of osteoclast-targeted therapy and (6) global access to prostate cancer drugs. There were 101 consensus questions, consisting of 91 questions from APCCC 2017 and 10 new questions from MyAPCCC 2018, selected and modified by the steering committee; of which, 23 questions were assessed in both ideal world and real-world settings. A panel of 22 experts, comprising of 11 urologists and 11 oncologists, voted on 101 predefined questions anonymously. Final voting results were compared with the APCCC 2017 outcomes.

resultsMost voting results from the MyAPCCC 2018 were consistent with the APCCC 2017 outcomes. No consensus was achieved for controversial topics with little level I evidence, such as management of oligometastatic disease. No consensus was reached on using high-cost drugs in castration-naïve or castration-resistant metastatic prostate cancer in real-world settings. All panellists recommended using generic drugs when available.

conclusionsThe MyAPCCC 2018 voting results reflect the management of advanced prostate cancer in a middle-income country in a real-world setting. These results may serve as a guide for local clinical practices and highlight the financial challenges in modern healthcare.

Indexed as

Prostatic NeoplasmsSocieties, MedicalConsensus Statements as TopicHealth Services AccessibilityHumansMalaysiaMalecastration-naïve prostate cancercastration-resistant prostate cancercost and access to treatmenthigh-risk localized prostate cancerlow-middle income countriesoligometastatic prostate cancer#pcsm#ProstateCancer

Identifiers

PMID31077523
PMCPMC6851975
OpenAlexW2944090322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.