Evidence map›Paper›PMID 31077477›Full record

ArticleJournal of magnetic resonance imaging : JMRI2019

Ungated nonenhanced radial quiescent interval slice-selective (QISS) magnetic resonance angiography of the neck: Evaluation of image quality.

Ioannis Koktzoglou, Emily A Aherne, Matthew T Walker, Joel R Meyer, Robert R Edelman

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ioannis KoktzoglouDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.ORCID 0000-0001-9335-2010
Emily A AherneDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
Matthew T WalkerDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
Joel R MeyerDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
Robert R EdelmanDepartment of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA.
NorthShore University HealthSystem · USNorthwestern University · US

Funding

Rapid Real-Time MR Angiography of Suspected StrokeR01EB027475 · NIBIB · ENDEAVOR HEALTH CLINICAL OPERATIONS · PI KOKTZOGLOU, IOANNIS · 2018 to 2021
$1.9M
NIBIB NIH HHS R01 EB027475
6 · The paper itself

Abstract

backgroundStandard-of-care time-of-flight (TOF) techniques for nonenhanced magnetic resonance angiography (NEMRA) of the carotid bifurcation and other cervical arteries often provide nondiagnostic image quality due to motion and flow artifacts. PURPOSE: To perform an initial evaluation of an ungated radial quiescent-interval slice-selective (QISS) technique for NEMRA of the neck, in comparison with 2D TOF and contrast-enhanced magnetic resonance angiography (CEMRA). STUDY TYPE: Retrospective. POPULATION: Sixty patients referred for neck MR angiography. FIELD STRENGTH/SEQUENCE: Ungated radial QISS at 3T. ASSESSMENT: Three radiologists scored image quality of 18 arterial segments using a 4-point scale (1, nondiagnostic; 2, fair; 3, good; 4, excellent), and two radiologists graded proximal internal carotid stenosis using five categories (<50%, 50-69%, 70-99%, occlusion, nondiagnostic). STATISTICAL TESTS: Friedman tests with post-hoc Wilcoxon signed-rank tests; unweighted Gwet's AC1 statistic; tests for equality of proportions.

resultsUngated radial QISS provided image quality that significantly exceeded 2D TOF (mean scores of 2.7 vs. 2.0, 2.7 vs. 2.2, and 2.9 vs. 2.3; P < 0.001, all comparisons), while CEMRA provided the best image quality (mean scores of 3.6, 3.7, and 3.5 for the three reviewers). Interrater agreement of image quality scores was substantial for CEMRA (AC1 = 0.70, P < 0.001), and moderate for QISS (AC1 = 0.43, P < 0.001) and TOF (AC1 = 0.41, P < 0.001). Compared with TOF, QISS NEMRA provided a significantly higher percentage of diagnostic segments for all three reviewers (91.0% vs. 71.7%, 93.5% vs. 72.9%, 95.5% vs. 85.2%; P < 0.0001) and demonstrated better agreement with CEMRA for grading of proximal internal carotid stenosis (AC1 = 0.94 vs. 0.73 for reviewer 1, P < 0.05; AC1 = 0.89 vs. 0.68 for reviewer 2, P < 0.05). DATA

conclusionIn this initial study, ungated radial QISS significantly outperformed 2D TOF for the evaluation of the neck arteries, with overall better image quality and more diagnostic arterial segments, and improved agreement with CEMRA for grading stenosis of the proximal internal carotid artery. LEVEL OF EVIDENCE: 3 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2019;50:1798-1807.

Indexed as

Carotid StenosisContrast MediaEvaluation Studies as TopicGated Blood-Pool ImagingHumansImage EnhancementMagnetic Resonance AngiographyNeckObserver VariationReproducibility of ResultsRetrospective StudiesContrast Mediacarotid bifurcationmagnetic resonance angiographynecknonenhancedquiescent-interval slice-selective (QISS)time-of-flight

Identifiers

PMID31077477
PMCPMC7101236
OpenAlexW2944621783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.