Evidence map›Paper›PMID 31077420›Full record

ArticleThe Prostate2019

Association among plasma 1,25(OH)

Swathi Ramakrishnan, Susan E Steck, Lenore Arab, Hongmei Zhang, Jeannette T Bensen, Elizabeth T H Fontham, Candace S Johnson, James L Mohler, Gary J Smith, L Joseph Su and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Prostate, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Cancer prevention: past challenges and future directions.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Immune Response: A Missed Opportunity Between Vitamin D and Radiotherapy.Frontiers in cell and developmental biology · 2021
    Review
  10. Combination of statin/vitamin D and metastatic castration-resistant prostate cancer (CRPC): a post hoc analysis of two randomized clinical trials.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Article
  11. Article
  12. Review
  13. Vitamin D, gut microbiota, and radiation-related resistance: a love-hate triangle.Journal of experimental & clinical cancer research : CR · 2019
    Review
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Swathi RamakrishnanDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Susan E SteckDepartment of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.
Lenore ArabDavid Geffen School of Medicine, University of California, Los Angeles, California.
Hongmei ZhangDivision of Epidemiology, Biostatistics, and Environmental Health, University of Memphis, Memphis, Tennessee.
Jeannette T BensenDepartment of Epidemiology, Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Elizabeth T H FonthamSchool of Public Health, Louisiana State University Health Sciences Center, New Orleans, Louisiana.
Candace S JohnsonDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
James L MohlerDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.ORCID 0000-0002-7726-3795
Gary J SmithDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
L Joseph SuWinthrop P. Rockefeller Cancer Institute, Department of Epidemiology, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Anna WoloszynskaDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, New York.ORCID 0000-0001-5279-9414
Roswell Park Comprehensive Cancer Center · USLouisiana State University Health Sciences Center New Orleans · USUniversity of California, Los Angeles · USUniversity of Memphis · USUniversity of North Carolina at Chapel Hill · USUniversity of South Carolina · USWinthrop Rockefeller Foundation · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
ANTITUMOR MECHANISMS &THERAPEUTIC EFFECTS OF VITAMIN DR01CA067267 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHNSON, CANDACE S, TRUMP, DONALD L · 1995 to 2013
$5.7M
Vitamin D and Breast Cancer BiomarkersR21CA137650 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WOOD, MARIE E. · 2010 to 2011
$618k
NCI NIH HHS P30 CA016056NCI NIH HHS R01 CA067267NCI NIH HHS R21 CA137650NIH HHS CA016056NIH HHS CA067267NIH HHS CA137650
6 · The paper itself

Abstract

backgroundAfrican-American (AA) men tend to present with more aggressive prostate cancer (Gleason score >7) than European-American (EA) men. Vitamin D and its metabolites are implicated in prostate cancer biology with vitamin D deficiency, indicated by its metabolite levels in serum or plasma, usually observed in AA men.

objectiveTo determine if 1, 25-dihydroxy vitamin D3 [1,25(OH)

designResearch subjects from the North Carolina-Louisiana Prostate Cancer Project (AA n = 435 and EA n = 532) were included. Plasma metabolites 1,25(OH)

resultsResearch subjects in the second and third tertiles of plasma levels of 1, 25(OH)

conclusionsThe 1,25(OH)

Indexed as

AgedCalcitriolHumansMaleMiddle AgedNeoplasm GradingNeoplasm InvasivenessProstateProstatic NeoplasmsRisk FactorsVitamin D25-hydroxyvitamin DCalcitriolVitamin Dprostate cancerracial disparitiesvitamin D

Identifiers

PMID31077420
PMCPMC6593756
OpenAlexW2944743112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.