Evidence map›Paper›PMID 31077275›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2019

Helping GPs to extrapolate guideline recommendations to patients for whom there are no explicit recommendations, through the visualization of drug properties. The example of AntibioHelp® in bacterial diseases.

Rosy Tsopra, Karima Sedki, Mélanie Courtine, Hector Falcoff, Antoine De Beco, Ronni Madar, Frédéric Mechaï, Jean-Baptiste Lamy

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  7. Need for innovation in electronic health record-based medication alerts.Journal of the American Medical Informatics Association : JAMIA · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rosy TsopraUniversité Paris 13, SMBH, Bobigny, France.
Karima SedkiLIMICS, Université Paris 13, Sorbonne Université, Inserm, Bobigny, France.
Mélanie CourtineLIMICS, Université Paris 13, Sorbonne Université, Inserm, Bobigny, France.
Hector FalcoffSociété de Formation Thérapeutique du Généraliste (SFTG), Paris, France.
Antoine De BecoSociété de Formation Thérapeutique du Généraliste (SFTG), Paris, France.
Ronni MadarUniversité Paris 13, SMBH, Bobigny, France.
Frédéric MechaïAP-HP, Hôpital Avicenne, Service de Maladies Infectieuses, Bobigny, F93000, France.
Jean-Baptiste LamyLIMICS, Université Paris 13, Sorbonne Université, Inserm, Bobigny, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionClinical decision support systems (CDSS) implementing clinical practice guidelines (CPGs) have 2 main limitations: they target only patients for whom CPGs provide explicit recommendations, and their rationale may be difficult to understand. These 2 limitations result in poor CDSS adoption. We designed AntibioHelp® as a CDSS for antibiotic treatment. It displays the recommended and nonrecommended antibiotics, together with their properties, weighted by degree of importance as outlined in the CPGs. The aim of this study was to determine whether AntibioHelp® could increase the confidence of general practitioners (GPs) in CPG recommendations and help them to extrapolate guidelines to patients for whom CPGs provide no explicit recommendations. MATERIALS AND

methodsWe carried out a 2-stage crossover study in which GPs responded to clinical cases using CPG recommendations either alone or with explanations displayed through AntibioHelp®. We compared error rates, confidence levels, and response times.

resultsWe included 64 GPs. When no explicit recommendation existed for a particular situation, AntibioHelp® significantly decreased the error rate (-41%, P value = 6x10-13), and significantly increased GP confidence (+8%, P value = .02). This CDSS was considered to be usable by GPs (SUS score = 64), despite a longer interaction time (+9-22 seconds). By contrast, AntibioHelp® had no significant effect if there was an explicit recommendation. DISCUSSION/

conclusionThe visualization of weighted antibiotic properties helps GPs to extrapolate recommendations to patients for whom CPGs provide no explicit recommendations. It also increases GP confidence in their prescriptions for these patients. Further evaluations are required to determine the impact of AntibioHelp® on antibiotic prescriptions in real clinical practice.

Indexed as

Data DisplayDecision Support Systems, ClinicalPractice Guidelines as TopicAdultAgedAnti-Bacterial AgentsAttitude of Health PersonnelBacterial InfectionsCross-Over StudiesEvidence-Based MedicineFemaleGeneral PractitionersHumansMaleMedication ErrorsMiddle AgedAnti-Bacterial Agentsantibioticsclinical decision support systemclinical practice guidelinesinfectious diseasesprimary carevisualization

Identifiers

PMID31077275
PMCPMC7647204

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.