Evidence map›Paper›PMID 31076999›Full record

ArticleNeurotoxicity research2019

Naringenin Inhibit the Hydrogen Peroxide-Induced SH-SY5Y Cells Injury Through Nrf2/HO-1 Pathway.

Yuzi Jin, Hua Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  8. Review
  9. Review
  10. VANL-100 Attenuates Beta-Amyloid-Induced Toxicity in SH-SY5Y Cells.International journal of molecular sciences · 2022
    Article
  11. Article
  12. Article
  13. Remedying the Mitochondria to Cure Human Diseases by Natural Products.Oxidative medicine and cellular longevity · 2020
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuzi JinDepartment of Pediatrics, Shengjing Hospital, China Medical University, No. 36 Sanhao Street, Shenyang, 110004, China.
Hua WangDepartment of Pediatrics, Shengjing Hospital, China Medical University, No. 36 Sanhao Street, Shenyang, 110004, China. wangh1@sj-hospital.org.
China Medical University · CN

Funding

National Key Research and Development Program of China 2016YFC1306203
6 · The paper itself

Abstract

Naringenin (NGN), a flavonoid, abundantly present in citrus fruits, has been established as a neuroprotective agent. However, the precise protective mechanisms remain worthy of further investigation. The present study was designed to explore the protective effects of NGN against hydrogen peroxide (H

Indexed as

AntioxidantsApoptosisCell Line, TumorCell SurvivalFlavanonesHeme Oxygenase-1HumansHydrogen PeroxideMembrane Potential, MitochondrialNeuroprotective AgentsNF-E2-Related Factor 2Reactive Oxygen SpeciesSignal TransductionAntioxidantsFlavanonesHeme Oxygenase-1HMOX1 protein, humanHydrogen PeroxidenaringeninNeuroprotective AgentsNFE2L2 protein, humanNF-E2-Related Factor 2Reactive Oxygen SpeciesHeme oxygenase-1NaringeninNeuroprotectionNrf2Oxidative stress

Identifiers

PMID31076999
OpenAlexW2944063765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.