ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2019
A practical guide to active stand testing and analysis using continuous beat-to-beat non-invasive blood pressure monitoring.
Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05566379 (Effects of a Mindfulness Intervention on Physical and Psychological Well-Being and Quality of Life in Patients With Post Acute Sequelae of SARS-CoV-2 Infection), which is not on this map. Cited by 70 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of a Mindfulness Intervention on Physical and Psychological Well-Being and Quality of Life in Patients With Post Acute Sequelae of SARS-CoV-2 Infection (PASC) Dysautonomia
Who cites it
70 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cardiovascular Disorders and Falls Among Older Adults: A Systematic Review and Meta-Analysis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Pooled it
- Prevalence of initial orthostatic hypotension in older adults: a systematic review and meta-analysis.Age and ageing · 2021Pooled it
- Functional Limitations and Exercise Intolerance in Patients With Post-COVID Condition: A Randomized Crossover Clinical Trial.JAMA network open · 2024Trial
- Orthostatic Blood Pressure Recovery Is Associated With the Rate of Cognitive Decline and Mortality in Clinical Alzheimer's Disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Trial
- A Closed-Loop Cardiovascular Model of the Supine-To-Stand Manoeuvre: Implications for Falls.International journal for numerical methods in biomedical engineering · 2026Article
- The combined association of STOPPFall medication use and orthostatic blood pressure abnormalities with future falls and fractures in community-dwelling older people.European geriatric medicine · 2026Article
- Coefficient of variation of R-R intervals during deep breathing as a risk marker of orthostatic blood pressure decline in patients with Type 2 diabetes mellitus.Nagoya journal of medical science · 2026Article
- Could the monocyte-to-high-density lipoprotein cholesterol ratio serve as a reliable marker for orthostatic hypotension in older adults? A cross-sectional study.BMC geriatrics · 2026Observational
- Linguistic validation and reliability of the Brazilian Portuguese version of the Composite Autonomic Symptom Score 31 (COMPASS 31).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Prevalence of initial orthostatic hypotension in geriatric inpatients: the role of time to stand.European geriatric medicine · 2026Article
- Unveiling orthostatic hypotension in precapillary pulmonary hypertension.ERJ open research · 2026Article
- Uncontrolled Orthostatic Hypotension and Multi-channel Cerebral Hemodynamic Changes in a Young Male Participant: A Case Report.Advances in experimental medicine and biology · 2026Article
- Responses to active stand test predict 12-year incident cardiovascular disease and mortality.Communications medicine · 2025Article
- Autonomic Cardiovascular Assessment in Obstructive Sleep Apnea Using Beat-to-Beat Blood Pressure: A Pilot Study.Sleep science (Sao Paulo, Brazil) · 2025Article
- The association between STOPPFall medication use and orthostatic hypotension in community-dwelling older people.Age and ageing · 2025Article
- Using Active Standing Orthostatic Stress Test to Assess Physiological Responses in Individuals with Long COVID: A Systematic Review.Journal of clinical medicine · 2025Review
- The feasibility of a set of physical resilience measurements in older patients admitted to the acute medical unit.BMC geriatrics · 2025Article
- Changes in Autonomic Balance, Cardiac Parasympathetic Modulation, and Cardiac Baroreflex Gain in Older Adults Under Different Orthostatic Stress Conditions.Healthcare (Basel, Switzerland) · 2025Article
- Hemodynamic and autonomic dysfunction in symptomatic carotid artery stenosis.Clinical physiology and functional imaging · 2025Article
- Bioimpedance-Derived Phase Angle Was Associated with Faster Blood Pressure Stabilisation Following Orthostatic Challenge in Older Adults.Journal of frailty, sarcopenia and falls · 2025Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe average adult stands approximately 50-60 times per day. Cardiovascular responses evoked during the first 3 min of active standing provide a simple means to clinically assess short-term neural and cardiovascular function across the lifespan. Clinically, this response is used to identify the haemodynamic correlates of patient symptoms and attributable causes of (pre-)syncope, and to detect autonomic dysfunction, variants of orthostatic hypotension, postural orthostatic tachycardia syndrome and orthostatic hypertension.
methodsThis paper provides a set of experience/expertise-based recommendations detailing current state-of-the-art measurement and analysis approaches for the active stand test, focusing on beat-to-beat BP technologies. This information is targeted at those interested in performing and interpreting the active stand test to current international standards.
resultsThis paper presents a practical step-by-step guide on (1) how to perform active stand measurements using beat-to-beat continuous blood pressure measurement technologies, (2) how to conduct an analysis of the active stand response and (3) how to identify the spectrum of abnormal blood pressure and heart rate responses which are of clinical interest.
conclusionImpairments in neurocardiovascular control are an attributable cause of falls and syncope across the lifespan. The simple active stand test provides the clinician with a powerful tool for assessing individuals at risk of such common disorders. However, its simplicity belies the complexity of its interpretation. Care must therefore be taken in administering and interpreting the test in order to maximise its clinical benefit and minimise its misinterpretation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.