Evidence map›Paper›PMID 31076559›Full record

ArticleAging2019

Magnesium transporter protein solute carrier family 41 member 1 suppresses human pancreatic ductal adenocarcinoma through magnesium-dependent Akt/mTOR inhibition and bax-associated mitochondrial apoptosis.

Jing Xie, Chien-Shan Cheng, Xiao Yan Zhu, Ye Hua Shen, Li Bin Song, Hao Chen, Zhen Chen, Lu Ming Liu, Zhi Qiang Meng

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 33 citations in OpenAlex.

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  17. Ionic Regulation of T-Cell Function and Anti-Tumour Immunity.International journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jing XieDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Chien-Shan ChengDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Xiao Yan ZhuDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Ye Hua ShenDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Li Bin SongDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Hao ChenDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Zhen ChenDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Lu Ming LiuDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Zhi Qiang MengDepartment of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China.
Fudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to identify the function of the Mg

Indexed as

AnimalsApoproteinsbcl-2-Associated X ProteinCarcinoma, Pancreatic DuctalCation Transport ProteinsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMembrane Potential, MitochondrialMiceMitochondriamTOR Associated Protein, LST8 HomologNeoplasm StagingPancreatic NeoplasmsApoproteinsbcl-2-Associated X ProteinCation Transport ProteinsmTOR Associated Protein, LST8 HomologProto-Oncogene Proteins c-aktSLC41A1 protein, humanage-related diseaseagingAkt/mTORapoptosismitochondira membrane potentialpancreatic ductal adenocarcinomaROSSLC41A1

Identifiers

PMID31076559
PMCPMC6535063
OpenAlexW2944504698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.