Evidence map›Paper›PMID 31076551›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Andrew Santiago-Frangos, Kathrin S Fröhlich, Jeliazko R Jeliazkov, Ewelina M Małecka, Giada Marino, Jeffrey J Gray, Ben F Luisi, Sarah A Woodson, Steven W Hardwick

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Competition for Hfq drives kinetic selection of mRNA targets byProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Intrinsically disordered interaction network in an RNA chaperone revealed by native mass spectrometry.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Structural basis of rotavirus RNA chaperone displacement and RNA annealing.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Differential Chromosome- and Plasmid-Borne Resistance ofInternational journal of molecular sciences · 2021
    Article
  14. Impacts of Small RNAs and Their Chaperones on Bacterial Pathogenicity.Frontiers in cellular and infection microbiology · 2021
    Review
  15. Switching fatty acid metabolism by an RNA-controlled feed forward loop.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Andrew Santiago-FrangosCell, Molecular and Developmental Biology and Biophysics Program, Johns Hopkins University, Baltimore, MD 21218.
Kathrin S FröhlichDepartment of Biology I, Microbiology, Ludwig Maximilian University Munich, 82152 Martinsried, Germany.
Jeliazko R JeliazkovProgram in Molecular Biophysics, Johns Hopkins University, Baltimore, MD 21218.
Ewelina M MałeckaThomas C. Jenkins Department of Biophysics, Johns Hopkins University, Baltimore, MD 21218.
Giada MarinoDepartment of Biology I, Plant Molecular Biology, Ludwig Maximilian University Munich, 82152 Martinsried, Germany.ORCID 0000-0002-1525-4244
Jeffrey J GrayProgram in Molecular Biophysics, Johns Hopkins University, Baltimore, MD 21218.ORCID 0000-0001-6380-2324
Ben F LuisiDepartment of Biochemistry, University of Cambridge, CB2 1GA Cambridge, United Kingdom bfl20@cam.ac.uk swoodson@jhu.edu swh32@cam.ac.uk.
Sarah A WoodsonCell, Molecular and Developmental Biology and Biophysics Program, Johns Hopkins University, Baltimore, MD 21218; bfl20@cam.ac.uk swoodson@jhu.edu swh32@cam.ac.uk.ORCID 0000-0003-0170-1987
Steven W HardwickDepartment of Biochemistry, University of Cambridge, CB2 1GA Cambridge, United Kingdom bfl20@cam.ac.uk swoodson@jhu.edu swh32@cam.ac.uk.ORCID 0000-0001-9246-1864
Johns Hopkins University · USLudwig-Maximilians-Universität München · DEUniversity of Cambridge · GB

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Assembly Mechanisms of RNA-Protein Complexes for Genetic ControlR35GM136351 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI SARAH A. WOODSON · 2020 to 2026
$4.4M
Prediction of the Structure of Therapeutic Antibodies with their AntigensR01GM078221 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GRAY, JEFFREY J · 2006 to 2020
$4.0M
Hfq RNA Chaperone and the Mechanism of RNA-Dependent RegulationR01GM120425 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI WOODSON, SARAH A. · 2016 to 2019
$1.3M
Computational Design of Crystal Lattice Interactions to Determine Recalcitrant Protein StructuresF31GM123616 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI JELIAZKOV, JELIAZKO · 2017 to 2018
$81k
NIGMS NIH HHS F31 GM123616NIGMS NIH HHS R01 GM078221NIGMS NIH HHS R01 GM120425NIGMS NIH HHS R35 GM136351NIGMS NIH HHS T32 GM007231Wellcome TrustWellcome Trust 200873/Z/16/Z
6 · The paper itself

Abstract

We have solved the X-ray crystal structure of the RNA chaperone protein Hfq from the alpha-proteobacterium

Indexed as

Bacterial ProteinsCaulobacter crescentusHost Factor 1 ProteinRNA, BacterialCrystallography, X-RayModels, MolecularMolecular ChaperonesProtein BindingRNA, MessengerRNA, Small UntranslatedBacterial ProteinsHost Factor 1 ProteinMolecular ChaperonesRNA, BacterialRNA, MessengerRNA, Small UntranslatedCaulobacterHfqnatively unstructured proteinRNA–protein interactionsRNA

Identifiers

PMID31076551
PMCPMC6561178
OpenAlexW2943485734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.