Evidence map›Paper›PMID 31076531›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding.

Zehui Qu, Zibin Li, Lizhen Ma, Xiaohui Wei, Lijie Zhang, Ruiying Liang, Geng Meng, Nianzhi Zhang, Chun Xia

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zehui QuDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China.ORCID 0000-0002-4530-5428
Zibin LiDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China.ORCID 0000-0001-7291-0423
Lizhen MaDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China.ORCID 0000-0002-8259-2972
Xiaohui WeiDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China.ORCID 0000-0001-6660-0242
Lijie ZhangDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China.ORCID 0000-0003-0932-8523
Ruiying LiangDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China.ORCID 0000-0002-3377-4390
Geng MengDepartment of Veterinary Biomedicine, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China; and.
Nianzhi ZhangDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China; zhangnianzhi@cau.edu.cn xiachun@cau.edu.cn.
Chun XiaDepartment of Microbiology and Immunology, College of Veterinary Medicine, China Agricultural University, Haidian District, Beijing 100094, China; zhangnianzhi@cau.edu.cn xiachun@cau.edu.cn.ORCID 0000-0002-3444-0624
China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bats are natural reservoir hosts, harboring more than 100 viruses, some of which are lethal to humans. The asymptomatic coexistence with viruses is thought to be connected to the unique immune system of bats. MHC class I (MHC I) presentation is closely related to cytotoxic lymphocyte immunity, which plays an important role in viral resistance. To investigate the characteristics of MHC I presentation in bats, the crystal structures of peptide-MHC I complexes of

Indexed as

AnimalsAntigen PresentationAntigensChiropteraCrystallography, X-RayHistocompatibility Antigens Class IImmunity, CellularMass SpectrometryModels, MolecularPeptide LibraryPeptidesProtein BindingAntigensHistocompatibility Antigens Class IPeptide LibraryPeptides

Identifiers

PMID31076531
PMCPMC6545463
OpenAlexW2944624531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.