Evidence map›Paper›PMID 31076437›Full record

ArticleApplied and environmental microbiology2019

Differences in Viral Disinfection Mechanisms as Revealed by Quantitative Transfection of Echovirus 11 Genomes.

Jason Torrey, Urs von Gunten, Tamar Kohn

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

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  15. Ozone potential to fight against SAR-COV-2 pandemic: facts and research needs.Environmental science and pollution research international · 2021
    Review
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  17. Article
  18. Review
  19. Article
  20. Enveloped Virus Inactivation on Personal Protective Equipment by Exposure to Ozone.medRxiv : the preprint server for health sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jason TorreyLaboratory of Environmental Chemistry, School of Architecture, Civil and Environmental Engineering (ENAC), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID 0000-0002-1518-811X
Urs von GuntenLaboratory for Water Quality and Treatment, School of Architecture, Civil and Environmental Engineering (ENAC), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID 0000-0001-6852-8977
Tamar KohnLaboratory of Environmental Chemistry, School of Architecture, Civil and Environmental Engineering (ENAC), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland tamar.kohn@epfl.ch.ORCID 0000-0003-0395-6561
École Polytechnique Fédérale de Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virus inactivation mechanisms can be elucidated by methods that measure the loss of specific virus functionality (e.g., host attachment, genome internalization, and genome replication). Genome functionality is frequently assessed by PCR-based methods, which are indirect and potentially inaccurate; genome damage that affects detection by high-fidelity PCR enzymes may not adversely affect the ability of actual cellular enzymes to produce functional virus. Therefore, we developed here a transfection-based assay to quantitatively determine viral genome functionality by inserting viral RNA into host cells directly to measure their ability to produce new functional viruses from damaged viral genomes. Echovirus 11 was treated with ozone, free chlorine (FC), UV light at 254 nm (UV

Indexed as

Genome, ViralVirus InactivationChlorineDisinfectantsDisinfectionEnterovirus B, HumanHot TemperatureOzonePolymerase Chain ReactionTransfectionUltraviolet RaysChlorineDisinfectantsOzonedisinfectionechovirus 11enterovirusfree chlorinegenome functionalitygenome integrityheat inactivationozonetransfectionUV254

Identifiers

PMID31076437
PMCPMC6606871
OpenAlexW2945236522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.