ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2019
Association of Kidney Transplant Center Volume With 3-Year Clinical Outcomes.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Understanding frailty across the kidney transplant continuum: a comprehensive systematic review of recent evidence.International urology and nephrology · 2026Pooled it
- Impact of Cold Ischemia Time on Allograft Survival and Policy.Kidney international reports · 2026Article
- Induction therapy in kidney transplant recipients: A consensus statement of Indian Society of Organ Transplantation.World journal of transplantation · 2026Review
- The Caseload Requirement for Renal Transplantation—An Analysis of German Hospital Quality Assurance Data from 2013–2021.Deutsches Arzteblatt international · 2024Article
- Twelve Thousand Kidney Transplants Over More Than 55 Y: A Single-center Experience.Transplantation direct · 2024Article
- "Long-term effects of center volume on transplant outcomes in adult kidney transplant recipients".PloS one · 2024Article
- Kidney transplantation in Icelandic patients, 2000-2019: are outcomes affected by low volume?Frontiers in transplantation · 2024Article
- Factors Underlying Racial Disparity in Utilization of Hepatitis C-Viremic Kidneys in the United States.Journal of racial and ethnic health disparities · 2023Article
- Impact of institutional case volume of solid organ transplantation on patient outcomes and implications for healthcare policy in Korea.Korean journal of transplantation · 2023Review
- Simultaneous Heart-Kidney Transplant-Does Hospital Experience With Heart Transplant or Kidney Transplant Have a Greater Impact on Patient Outcomes?Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Predictive Value of HAS-BLED Score Regarding Bleeding Events and Graft Survival following Renal Transplantation.Journal of clinical medicine · 2022Article
- Major Variation across Local Transplant Centers in Probability of Kidney Transplant for Wait-Listed Patients.Journal of the American Society of Nephrology : JASN · 2020Article
- Article
- The State of Pediatric Kidney Transplantation in India: A Survey-based Analysis of Practices, Challenges, and Educational Needs.Journal of Indian Association of Pediatric SurgeonsArticle
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7 authors at 1 institution in 1 country.
Funding
Abstract
RATIONALE &
objectiveA robust relationship between procedure volume and clinical outcomes has been demonstrated across many surgical fields. This study assessed whether a center volume-outcome relationship exists for contemporary kidney transplantation, specifically for diabetic recipients, older recipients (aged ≥65 years), and recipients of high kidney donor profile index (KDPI ≥ 85) kidneys. STUDY
designRetrospective cohort study. SETTING &
participantsAdult kidney-only transplant recipients who underwent transplantation between 2009 and 2013 (N = 79,581). EXPOSURES: The primary exposure variable was center volume, categorized into quartiles based on the total kidney transplantation volume. Quartile 1 (Q1) centers performed a mean of fewer than 66 kidney transplantations per year, whereas Q4 centers performed a mean of more than 196 kidney transplantations per year. OUTCOMES: All-cause graft failure and mortality within 3 years of transplantation. ANALYTICAL APPROACH: Multivariable Cox frailty models were used to adjust for donor characteristics, recipient characteristics, and cold ischemia time.
resultsMinor differences in rates of 3-year deceased donor all-cause graft failure across quartiles of center volume were observed (14.9% for Q1 vs 16.7% for Q4), including in subgroups (diabetic recipients, 18.4% for Q1 vs 19.7% for Q4; older recipients, 19.4% for Q1 vs 22.5% for Q4; recipients of high KDPI kidneys, 26.5% for Q1 vs 26.5% for Q4). Results were similar for 3-year mortality. After adjustment for donor, recipient, and graft characteristics using Cox regression, center volume was not significantly associated with all-cause graft failure or mortality within 3 years, except that diabetic recipients at Q3 centers had slightly lower mortality (compared with Q1 centers, adjusted HR of 0.85 [95% CI, 0.73-0.99]). LIMITATIONS: Potential unmeasured confounding from patient comorbid conditions and organ selection.
conclusionsThese findings provide little evidence that care in higher volume centers is associated with better adjusted outcomes for kidney transplant recipients, even in populations anticipated to be at increased risk for graft failure or death.
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