Evidence map›Paper›PMID 31076014›Full record

ReviewCognitive neuropsychology

How is electrical stimulation of the brain experienced, and how can we tell? Selected considerations on sensorimotor function and speech.

Kevin A Mazurek, Marc H Schieber

Abstract readReview
In one paragraph

Review in Cognitive neuropsychology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Blunted baroreflex-mediated sympathoinhibition and vasodilation to countdown before exercise in young women compared to men.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
  2. Injecting Information into the Mammalian Cortex: Progress, Challenges, and Promise.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kevin A MazurekDel Monte Institute for Neuroscience, University of Rochester , Rochester , NY , USA.ORCID 0000-0002-9002-2339
Marc H SchieberDel Monte Institute for Neuroscience, University of Rochester , Rochester , NY , USA.ORCID 0000-0002-4315-8161

Funding

Injecting instructions using intracortical microstimulation in association cortexR01NS107271 · NINDS · UNIVERSITY OF ROCHESTER · PI SCHIEBER, MARC H · 2018 to 2022
$2.1M
Voluntary control of neuronal activityR01NS092626 · NINDS · UNIVERSITY OF ROCHESTER · PI SCHIEBER, MARC H · 2015 to 2019
$1.9M
Delivering instructional microstimulation in frontal and parietal cortical areasF32NS093709 · NINDS · UNIVERSITY OF ROCHESTER · PI MAZUREK, KEVIN ANDREW · 2016 to 2017
$121k
NINDS NIH HHS F32 NS093709NINDS NIH HHS R01 NS092626NINDS NIH HHS R01 NS107271
6 · The paper itself

Abstract

Electrical stimulation of the nervous system is a powerful tool for localizing and examining the function of numerous brain regions. Delivered to certain regions of the cerebral cortex, electrical stimulation can evoke a variety of first-order effects, including observable movements or an urge to move, or somatosensory, visual, or auditory percepts. In still other regions the subject may be oblivious to the stimulation. Often overlooked, however, is whether the subject is aware of the stimulation, and if so, how the stimulation is experienced by the subject. In this review of how electrical stimulation has been used to study selected aspects of sensorimotor and language function, we raise questions that future studies might address concerning the subjects' second-order experiences of intention and agency regarding evoked movements, of the naturalness of evoked sensory percepts, and of other qualia that might be evoked in the absence of an overt first-order experience.

Indexed as

BrainElectric StimulationFemaleHumansMaleSomatosensory CortexSpeechCerebral cortexelectrical stimulationintracortical microstimulationperceptionsensation

Identifiers

PMID31076014
PMCPMC6744321

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.