Evidence map›Paper›PMID 31075949›Full record

SynthesisInternational journal of environmental research and public health2019

Once Resin Composites and Dental Sealants Release Bisphenol-A, How Might This Affect Our Clinical Management?-A Systematic Review.

Anabela Baptista Paula, Debbie Toste, Alfredo Marinho, Inês Amaro, Carlos-Miguel Marto, Ana Coelho, Manuel Marques-Ferreira, Eunice Carrilho

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anabela Baptista PaulaInstitute of Integrated Clinical Practice, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. anabelabppaula@sapo.pt.ORCID 0000-0001-6154-4173
Debbie TosteInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. debbie_toste@hotmail.com.
Alfredo MarinhoInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. alfredomarinho1996@hotmail.com.
Inês AmaroInstitute of Integrated Clinical Practice, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. ines.amaros@hotmail.com.
Carlos-Miguel MartoInstitute of Integrated Clinical Practice, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. mig-marto@hotmail.com.ORCID 0000-0001-9269-5417
Ana CoelhoInstitute of Integrated Clinical Practice, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. anasofiacoelho@gmail.com.ORCID 0000-0002-2924-7926
Manuel Marques-FerreiraInstitute of Endodontics, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. m.mferreira@netcabo.pt.
Eunice CarrilhoInstitute of Integrated Clinical Practice, Institute for Clinical and Biomedical Research (iCBR), area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. eunicecarrilho@gmail.com.ORCID 0000-0002-5759-5557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Bisphenol A (BPA) based dental resins are commonly used in preventive and reparative dentistry. Since some monomers may remain unpolymerized in the application of dental resin, they dissolve in the saliva. (2) Methods: The literature search was carried out in Pubmed, Cochrane and Embase databases. Randomized controlled trials, cohort studies and case-control studies that evaluated BPA levels in human urine, saliva and/or blood were included. (3) Results: The initial search had 5111 results. A total of 20 studies were included in the systematic review. Most studies showed an increase of the levels of bisphenol A 1 h after treatments with composite resins and dental sealants. One week after treatments the levels were decreased. (4) Conclusions: Some clinical precautions should be taken to decrease the release of BPA, namely the use of rubber dam, the immediate polishing of all resins used, or the use of glycerin gel to avoid non-polymerization of the last resin layer, and mouthwash after treatment. Another preventive measure in addition to the above-mentioned is the use of the smallest possible number of restorations or sealants, a maximum of four per appointment. These measures are even more important in children, adolescents and pregnant women.

Indexed as

Benzhydryl CompoundsPhenolsPit and Fissure SealantsResins, SyntheticAnimalsBisphenol A CompoundsCase-Control StudiesCohort StudiesHumansRandomized Controlled Trials as TopicBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenolsPit and Fissure SealantsResins, Syntheticbisphenol Adental sealantsendocrine disruptorenvironmental levelsexposuremonomerspreventionresin composites

Identifiers

PMID31075949
PMCPMC6539392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.