Evidence map›Paper›PMID 31075912›Full record

ReviewMaterials (Basel, Switzerland)2019

Terahertz Spectroscopy and Imaging: A Cutting-Edge Method for Diagnosing Digestive Cancers.

Mihai Danciu, Teodora Alexa-Stratulat, Cipriana Stefanescu, Gianina Dodi, Bogdan Ionel Tamba, Cosmin Teodor Mihai, Gabriela Dumitrita Stanciu, Andrei Luca, Irene Alexandra Spiridon, Loredana Beatrice Ungureanu and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Mihai DanciuPathology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. mihai.danciu@umfiasi.ro.ORCID 0000-0002-0194-7832
Teodora Alexa-StratulatMedical Oncology-Radiotherapy, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. teodora.alexa-stratulat@umfiasi.ro.
Cipriana StefanescuDepartment of Biophysics and Medical Physics-Nuclear Medicine, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. cipriana.stefanescu@umfiasi.ro.
Gianina DodiAdvanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. gianina.dodi@umfiasi.ro.ORCID 0000-0002-5551-6077
Bogdan Ionel TambaAdvanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. bogdan.tamba@umfiasi.ro.
Cosmin Teodor MihaiAdvanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. cosmin-teodor.mihai@umfiasi.ro.
Gabriela Dumitrita StanciuAdvanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. gabriela-dumitrita.s@umfiasi.ro.ORCID 0000-0003-4440-9628
Andrei LucaAdvanced Research and Development Center for Experimental Medicine (CEMEX), Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. andrei.g.luca@umfiasi.ro.
Irene Alexandra SpiridonPathology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. irenespiridon@yahoo.com.
Loredana Beatrice UngureanuPathology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. loredana.ungureanu81@gmail.com.
Victor IanolePathology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. ianole.victor@gmail.com.
Irina CiortescuGastroenterology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. irinaciortescu@yahoo.com.
Catalina MihaiGastroenterology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. catalinamihai@yahoo.com.
Gabriela StefanescuGastroenterology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. gabriela.stefanescu@gmail.com.
Ioan ChirilăEnvironmental Health, National Institute of Public Health, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. chirilaioan@yahoo.com.
Romeo CiobanuElectrical Engineering Faculty, Gheorghe Asachi Technical University of Iasi, 700050 Iasi, Romania. rciobanu@yahoo.com.
Vasile Liviu DrugGastroenterology Department, Grigore T. Popa University of Medicine and Pharmacy of Iasi, 700051 Iasi, Romania. vasidrug@email.com.
Grigore T. Popa University of Medicine and Pharmacy · ROGheorghe Asachi Technical University of Iași · RO

Funding

Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii PN-III-P2-2.1-PED-2016-1598, 245PE/2017
6 · The paper itself

Abstract

The Terahertz's wavelength is located between the microwave and the infrared region of the electromagnetic spectrum. Because it is non-ionizing and non-invasive, Terahertz (THz)-based detection represents a very attractive tool for repeated assessments, patient monitoring, and follow-up. Cancer acts as the second leading cause of death in many regions, and current predictions estimate a continuous increasing trend. Of all types of tumors, digestive cancers represent an important percentage and their incidence is expected to increase more rapidly than other tumor types due to unhealthy lifestyle habits. Because it can precisely differentiate between different types of molecules, depending on water content, the information obtained through THz-based scanning could have several uses in the management of cancer patients and, more importantly, in the early detection of different solid tumors. The purpose of this manuscript is to offer a comprehensive overview of current data available on THz-based detection for digestive cancers. It summarizes the characteristics of THz waves and their interaction with tissues and subsequently presents available THz-based technologies (THz spectroscopy, THz-tomography, and THZ-endoscope) and their potential for future clinical use. The third part of the review is focused on highlighting current in vitro and in vivo research progress in the field, for identifying specific digestive cancers known as oral, esophageal, gastric, colonic, hepatic, and pancreatic tumors.

Indexed as

cancer diagnosisdigestive cancerscreeningterahertz endoscopyterahertz spectroscopyterahertz tomography

Identifiers

PMID31075912
PMCPMC6539301
OpenAlexW2944600736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.