Evidence map›Paper›PMID 31075867›Full record

ArticleMolecules (Basel, Switzerland)2019

Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma.

Silvia Tampucci, Sara Carpi, Maria Digiacomo, Beatrice Polini, Stefano Fogli, Susi Burgalassi, Marco Macchia, Paola Nieri, Clementina Manera, Daniela Monti

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Silvia TampucciDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. silvia.tampucci@unipi.it.ORCID 0000-0002-8927-6083
Sara CarpiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. sara.carpi@unipi.it.ORCID 0000-0002-3291-9009
Maria DigiacomoDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. maria.digiacomo@unipi.it.ORCID 0000-0003-0653-6642
Beatrice PoliniDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. b.polini@studenti.unipi.it.
Stefano FogliDepartment of Clinical and Experimental Medicine, University of Pisa, Via Savi 10, 56126 Pisa, Italy. stefano.fogli@unipi.it.
Susi BurgalassiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. susi.burgalassi@unipi.it.ORCID 0000-0002-0795-2886
Marco MacchiaDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. marco.macchia@unipi.it.
Paola NieriDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. Paola.nieri@unipi.it.
Clementina ManeraDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. clementina.manera@unipi.it.
Daniela MontiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy. daniela.monti@unipi.it.ORCID 0000-0001-7622-4367

Funding

Progetti di ricerca di Ateneo of the University of Pisa PRA_2017_51; PRA_2018_20
6 · The paper itself

Abstract

In this work, hybrid compounds

Indexed as

AnimalsCarcinoma, Squamous CellCell LineCell ProliferationCell SurvivalDiclofenacHumansInhibitory Concentration 50Keratosis, ActinicMicellesNanoparticlesParticle SizeSkin NeoplasmsSwineDiclofenacMicellesactinic keratosisantiproliferative activitydiclofenachybridin vitro skin permeation/penetrationnanomicellessquamous cell carcinoma

Identifiers

PMID31075867
PMCPMC6539072

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.