ArticleBiomolecules2019
Laboratory-Scale Isolation of Insect Antifreeze Protein for Cryobiology.
Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- Structure-Guided Discovery of a Cold-Responsive Antifreeze-like Protein from AntarcticMicroorganisms · 2026Article
- Winter-active spiders (Clubiona) have a hyperactive antifreeze protein with a unique beta-solenoid fold.The FEBS journal · 2026Article
- The effect of temperature and nitrogen source modulation on Pseudomonas fluorescens AQP671 ice recrystallization inhibition activity.PloS one · 2025Article
- Extended Temperature Range of the Ice-Binding Protein Activity.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Functional aggregation of cell-free proteins enables fungal ice nucleation.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Polyproline type II helical antifreeze proteins are widespread in Collembola and likely originated over 400 million years ago in the Ordovician Period.Scientific reports · 2023Article
- Bioinspired Threonine-Based Polymers with Potent Ice Recrystallization Inhibition Activity.ACS applied polymer materials · 2022Article
- Ice-binding proteins and bioinspired synthetic mimics in non-physiological environments.iScience · 2022Review
- Toward Understanding Bacterial Ice Nucleation.The journal of physical chemistry. B · 2022Article
- Structural diversity of marine anti-freezing proteins, properties and potential applications: a review.Bioresources and bioprocessing · 2022Review
- Subzero Nonfreezing Hypothermia with Insect Antifreeze Protein Dramatically Improves Survival Rate of Mammalian Cells.International journal of molecular sciences · 2021Article
- Membranes Are Decisive for Maximum Freezing Efficiency of Bacterial Ice Nucleators.The journal of physical chemistry letters · 2021Article
- A minimalistic cyclic ice-binding peptide from phage display.Nature communications · 2021Article
- Article
- Antifreeze protein complements cryoprotective dehydration in the freeze-avoiding springtail Megaphorura arctica.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Micromolar concentrations of hyperactive antifreeze proteins (AFPs) from insects can prevent aqueous solutions from freezing down to at least -6 °C. To explore cryopreservation of cells, tissues and organs at these temperatures without ice formation, we have developed a protocol to reliably produce ultrapure
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.