Evidence map›Paper›PMID 31075706›Full record

Trial reportPsychiatry research2019

Improvement in anxiety and depression symptoms following cognitive behavior therapy for pediatric obsessive compulsive disorder.

Michelle Rozenman, John Piacentini, Joseph O'Neill, R Lindsey Bergman, Susanna Chang, Tara S Peris

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychiatry research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Review
  11. Anxiety and Metabolic Disorders: The Role of Botanicals.Current issues in molecular biology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michelle RozenmanUCLA Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USA. Electronic address: mrozenman@mednet.ucla.edu.
John PiacentiniUCLA Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USA.
Joseph O'NeillUCLA Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USA.
R Lindsey BergmanUCLA Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USA.
Susanna ChangUCLA Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USA.
Tara S PerisUCLA Semel Institute for Neuroscience & Human Behavior, Los Angeles, CA, USA.
UCLA Medical Center · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Cognitive-Behavioral Therapy & Glutametergic Neurometabolites in Pediatric OCDR01MH081864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI O'NEILL, JOSEPH, PIACENTINI, JOHN C. · 2008 to 2012
$3.0M
Family Focused Intervention for Pediatric Obsessive Compulsive DisorderK23MH085058 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PERIS, TARA S · 2009 to 2013
$835k
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR001881NIMH NIH HHS K23 MH085058NIMH NIH HHS R01 MH081864
6 · The paper itself

Abstract

Pediatric obsessive-compulsive disorder (OCD) co-occurs frequently with other mental health conditions, adding to the burden of disease and complexity of treatment. Cognitive behavioral therapy (CBT) is efficacious for both OCD and two of its most common comorbid conditions, anxiety and depression. Therefore, treating OCD may yield secondary benefits for anxiety and depressive symptomatology. This study examined whether anxiety and/or depression symptoms declined over the course of OCD treatment and, if so, whether improvements were secondary to reductions in OCD severity, impairment, and/or global treatment response. The sample consisted of 137 youths who received 12 sessions of manualized CBT and were assessed by independent evaluators. Mixed models analysis indicated that youth-reported anxiety and depression symptoms decreased in a linear fashion over the course of CBT, however these changes were not linked to specific improvements in OCD severity or impairment but to global ratings of treatment response. Results indicate that for youth with OCD, CBT may offer benefit for secondary anxiety and depression symptoms distinct from changes in primary symptoms. Understanding the mechanisms underlying carryover in CBT techniques is important for furthering transdiagnostic and/or treatment-sequencing strategies to address co-occurring anxiety and depression symptoms in pediatric OCD.

Indexed as

AdolescentAnxietyChildCognitive Behavioral TherapyDepressionFemaleHumansMaleNeurodevelopmental DisordersObsessive-Compulsive DisorderTreatment OutcomeAdolescentAnxietyChildDepressionObsessive-compulsive disorder

Identifiers

PMID31075706
PMCPMC7197731
OpenAlexW2939128316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.