Evidence map›Paper›PMID 31075594›Full record

ArticleThe Science of the total environment2019

Thyroid hormones and neurobehavioral functions among adolescents chronically exposed to groundwater with geogenic arsenic in Bangladesh.

Khalid M Khan, Faruque Parvez, R Thomas Zoeller, Barbara A Hocevar, Lisa M Kamendulis, Diane Rohlman, Mahbubul Eunus, Joseph Graziano

Open access · greenAbstract read
In one paragraph

Article in The Science of the total environment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Prolonged exposure to NaAsOArchives of toxicology · 2024
    Article
  7. Article
  8. Update of the risk assessment of inorganic arsenic in food.EFSA journal. European Food Safety Authority · 2024
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Khalid M KhanDepartment of Environmental and Occupational Health, School of Public Health, Indiana University-Bloomington, IN, USA. Electronic address: kmkhan@indiana.edu.
Faruque ParvezDepartment of Environmental Health, Mailman School of Public Health, Columbia University, New York, USA.
R Thomas ZoellerDepartment of Biology, University of Massachusetts Amherst, MA, USA.
Barbara A HocevarDepartment of Environmental and Occupational Health, School of Public Health, Indiana University-Bloomington, IN, USA.
Lisa M KamendulisDepartment of Environmental and Occupational Health, School of Public Health, Indiana University-Bloomington, IN, USA.
Diane RohlmanDepartment of Occupational and Environmental Health, College of Public Health, The University of Iowa, IA, USA.
Mahbubul EunusU-Chicago Research Bangladesh, Ltd., Dhaka, Bangladesh.
Joseph GrazianoDepartment of Environmental Health, Mailman School of Public Health, Columbia University, New York, USA.
Columbia University · USIndiana University Bloomington · USIndiana University Health · USUniversity of Chicago Research Bangladesh · BDUniversity of Iowa · USUniversity of Massachusetts Amherst · US

Funding

Training CoreP42ES010349 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA · 2000 to 2020
$53.6M
NIEHS NIH HHS P42 ES010349
6 · The paper itself

Abstract

Groundwater, the major source of drinking water in Bengal Delta Plain, is contaminated with geogenic arsenic (As) enrichment affecting millions of people. Children exposed to tubewell water containing As may be associated with thyroid dysfunction, which in turn may impact neurodevelopmental outcomes. However, data to support such relationship is sparse. The purpose of this study was to examine if chronic water As (WAs) from Holocene alluvial aquifers in this region was associated with serum thyroid hormone (TH) and if TH biomarkers were related to neurobehavioral (NB) performance in a group of adolescents. A sample of 32 healthy adolescents were randomly drawn from a child cohort in the Health Effects of Arsenic Longitudinal Study (HEALS) in Araihazar, Bangladesh. Half of these participants were consistently exposed to low WAs (<10 μg/L) and the remaining half had high WAs exposure (≥10 μg/L) since birth. Measurements included serum total triiodothyronine (tT

Indexed as

AdolescentAdolescent BehaviorArsenicBangladeshCohort StudiesEnvironmental ExposureFemaleHumansLongitudinal StudiesMaleNervous System DiseasesPilot ProjectsThyroid HormonesWater Pollutants, ChemicalArsenicThyroid HormonesWater Pollutants, ChemicalArsenic in aquiferDrinking water arsenicMechanism of neurotoxicityThyroid biomarkers

Identifiers

PMID31075594
PMCPMC6544172
OpenAlexW2943044502

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.