Evidence map›Paper›PMID 31075390›Full record

ArticleNeuroImage2019

RE: Warnings and caveats in brain controllability.

Fabio Pasqualetti, Shi Gu, Danielle S Bassett

Abstract readComment
PubMed Publisher
In one paragraph

Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Review
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  11. Structural Controllability Predicts Functional Patterns and Brain Stimulation Benefits Associated with Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Fabio PasqualettiDepartment of Mechanical Engineering, University of California at Riverside, USA. Electronic address: fabiopas@engr.ucr.edu.
Shi GuUniversity of Electronic Science and Technology of China, China. Electronic address: gus@sas.upenn.edu.
Danielle S BassettDepartments of Bioengineering, Physics & Astronomy, Neurology, Psychiatry, Electrical & Systems Engineering, University of Pennsylvania, USA. Electronic address: dsb@seas.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of network control theory to analyze the organization of white matter fibers in the human brain has the potential to enable mechanistic theories of cognition, and to inform the development of novel diagnostics and treatments for neurological disease and psychiatric disorders (Gu et al., 2015). The recent article (Tu et al., 2018) aims to challenge several of the contributions of (Gu et al., 2015), and particularly the conclusions that brain networks are theoretically controllable from single regions, and that brain networks feature no specific controllability profiles when compared to random network models. Here we provide additional theoretical arguments in support of (Gu et al., 2015) and against the results and methodologies used in (Tu et al., 2018), thus settling that (i) brain networks are controllable from a single region, (ii) brain networks require large control energy, and (iii) brain networks feature distinctive controllability properties with respect to a class of random network models.

Indexed as

BrainWhite MatterCognitionComputer SimulationHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.