Evidence map›Paper›PMID 31074837›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2019

Reproductive health sequelae among women who survived Ebola virus disease in Liberia.

Christine L Godwin, David A Wohl, William A Fischer Nd, Kavita Singh, Darrell A Hawks, Elizabeth E Devore, Jerry Brown

Open access · hybridAbstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Christine L GodwinDepartment of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
David A WohlDivision of Infectious Disease, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
William A Fischer NdDivision of Pulmonary and Critical Care Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Kavita SinghDepartment of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Darrell A HawksInstitute for Global Health & Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Elizabeth E DevoreChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Jerry BrownEternal Love Winning Africa Hospital, Monrovia, Liberia.
University of North Carolina at Chapel Hill · USBrigham and Women's Hospital · USFamily Health International 360 · USUniversity of Liberia · LR

Funding

Clinical Sequelae and Urogenital Viral Dynamics in Survivors of Ebola Virus DiseaseR01AI123535 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FISCHER, WILLIAM, WOHL, DAVID A · 2017 to 2021
$3.3M
Mentoring New Investigators in Criminal Justice HIV Prevention and TreatmentK24DA037101 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOHL, DAVID A · 2014 to 2018
$911k
Clinical Sequelae and Urogenital Viral Dynamics in Survivors of Ebola Virus DiseaseK23AI121516 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FISCHER, WILLIAM · 2016 to 2019
$783k
Bill & Melinda Gates FoundationNIAID NIH HHS K23 AI121516NIAID NIH HHS R01 AI123535NIDA NIH HHS K24 DA037101NIH HHSUniversity of North Carolina at Chapel Hill
6 · The paper itself

Abstract

objectiveTo estimate the incidence of failed pregnancy and menstrual irregularities among Liberian women who had survived Ebola virus disease (EVD) and to identify host-specific and disease-specific factors associated with these outcomes.

methodsA cross-sectional questionnaire-based study was conducted between August 10, 2016, and February 7, 2017. The study population comprised 111 women aged 18-45 years who had survived EVD and were enrolled in the Longitudinal Liberian Ebola Survivor study based at the Eternal Love Winning Africa Hospital, Monrovia, Liberia. Self-reported data on outcomes related to pregnancy and menstrual changes since recovery from EVD were collected.

resultsIn all, 29 (26.1%) of the participants had become pregnant since surviving EVD. Of the 23 women whose pregnancies continued to term, 10 (43.4%) reported live birth, 11 (47.8%) reported spontaneous abortion, and two (8.7%) reported stillbirth. Of the 105 women who reported having regular menstruation before EVD, 27 (29.0%) reported experiencing irregular menstruation for unknown reasons after EVD. In bivariate logistic models, no associations were found between failed pregnancy or irregular menstruation and any of the factors of interest.

conclusionsAdverse pregnancy outcomes and irregular menstruation were frequently reported among EVD survivors in Liberia.

Indexed as

Reproductive HealthAdolescentAdultCross-Sectional StudiesDisease OutbreaksFemaleHemorrhagic Fever, EbolaHumansLiberiaLogistic ModelsLongitudinal StudiesMiddle AgedOdds RatioPregnancyPregnancy OutcomeSelf ReportEbola virus diseaseLiberiaMenstruationPost-Ebola sequelaePregnancySpontaneous abortionStillbirthSurvivor

Identifiers

PMID31074837
PMCPMC6675397
OpenAlexW2944096062

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.