Evidence map›Paper›PMID 31074695›Full record

ArticleCBE life sciences education2019

Characterizing Students' Ideas about the Effects of a Mutation in a Noncoding Region of DNA.

Scott A Sieke, Betsy B McIntosh, Matthew M Steele, Jennifer K Knight

Abstract read
In one paragraph

Article in CBE life sciences education, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Introductory biology undergraduate students' mixed ideas about genetic information flow.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Scott A SiekeDepartment of Molecular, Cellular, and Developmental Biology, University of Colorado-Boulder, Boulder, CO 80309.
Betsy B McIntoshDepartment of Molecular, Cellular, and Developmental Biology, University of Colorado-Boulder, Boulder, CO 80309.
Matthew M SteeleCREATE for STEM Institute, Michigan State University, East Lansing, MI 48824.
Jennifer K KnightDepartment of Molecular, Cellular, and Developmental Biology, University of Colorado-Boulder, Boulder, CO 80309.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding student ideas in large-enrollment biology courses can be challenging, because easy-to-administer multiple-choice questions frequently do not fully capture the diversity of student ideas. As part of the Automated Analysis of Constructed Responses (AACR) project, we designed a question prompting students to describe the possible effects of a mutation in a noncoding region of DNA. We characterized answers from 1127 students enrolled in eight different large-enrollment introductory biology courses at three different institutions over five semesters and generated an analytic scoring system containing three categories of correct ideas and five categories of incorrect ideas. We iteratively developed a computer model for scoring student answers and tested the model before and after implementing an instructional activity designed to help a new set of students explore this concept. After completing a targeted activity and re-answering the question, students showed improvement from preassessment, with 64% of students in incorrect and 67% of students in partially incorrect (mixed) categories shifting to correct ideas only. This question, computer-scoring model, and instructional activity can now be reliably used by other instructors to better understand and characterize student ideas on the effects of mutations outside a gene-coding region.

Indexed as

StudentsBiologyDNA, IntergenicEducational MeasurementHumansLearningMutationUniversitiesDNA, Intergenic

Identifiers

PMID31074695
PMCPMC6755205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.