Evidence map›Paper›PMID 31074211›Full record

ReviewKorean circulation journal2019

The Past, Present and Future of Cardiac Resynchronization Therapy.

Thomas O'Brien, Myung Soo Park, Jong Chan Youn, Eugene S Chung

Registry-linked trialAbstract readReview
In one paragraph

Review in Korean circulation journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04463641 (Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04463641 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

Assessment of the Axone Micro Quadripolar Lead for Enhanced Cardiac Resynchronization Therapy

TypeinterventionalSponsorMicroPort CRMRan2020 to 2027Enrolled92ConditionsHeart Failure, Cardiac Resynchronization TherapyArmsImplantation of the Axone 4LV Lead
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas O'Brien *The Christ Hospital Heart and Vascular Center, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0002-0049-9345
Myung Soo Park *Division of Cardiology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.ORCID https://orcid.org/0000-0001-7832-4513
Jong Chan YounDivision of Cardiology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea. jong.chan.youn@gmail.com.ORCID https://orcid.org/0000-0003-0998-503X
Eugene S ChungThe Christ Hospital Heart and Vascular Center, Cincinnati, OH, USA.ORCID https://orcid.org/0000-0002-5406-8874

Funding

Hallym University HURF-2017-73Hallym University HURF-2018-31National Research Foundation of Korea NRF-2018R1C1B6005448
6 · The paper itself

Abstract

Cardiac resynchronization therapy (CRT) has revolutionized the care of the patients with heart failure with reduced ejection fraction and electrical dyssynchrony. The current guidelines for patient selection include measurement of left ventricular systolic function, QRS duration and morphology, and functional classification. Despite consistent and increasing evidence supporting CRT use in appropriate patients, CRT has been underutilized. Notwithstanding the heterogeneous definitions of non-response, more than one-third of patients demonstrate a lack of echocardiographic reverse remodeling or poor clinical outcome following CRT. Since the causes of this non-response are multifactorial, it will require multidisciplinary efforts to overcome including optimal patient selection, procedural strategies, as well as optimizing post-implant care in patients undergoing CRT. The innovations of novel pacing approaches combined with advanced imaging technologies may eventually offer a personalized CRT system uniquely tailored to each patient's dyssynchrony signature.

Indexed as

Cardiac resynchronization therapyCurrent statusFuture innovationsHeart failure

Identifiers

PMID31074211
PMCPMC6511527

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.