Evidence map›Paper›PMID 31074167›Full record

ArticleJournal of viral hepatitis2019

Perceived barriers related to testing, management and treatment of HCV infection among physicians prescribing opioid agonist therapy: The C-SCOPE Study.

Alain H Litwin, Martine Drolet, Chizoba Nwankwo, Martha Torrens, Andrej Kastelic, Stephan Walcher, Lorenzo Somaini, Emily Mulvihill, Jochen Ertl, Jason Grebely

Open access · hybridAbstract read
In one paragraph

Article in Journal of viral hepatitis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 7 countries.

Alain H LitwinDepartment of Medicine, University of South Carolina School of Medicine - Greenville and Prisma Health, Greenville, South Carolina.
Martine DroletMerck Canada Inc., Montreal, Canada.
Chizoba NwankwoMerck & Co., Inc., Kenilworth, New Jersey.
Martha TorrensDepartment of Psychiatry, Institut de Neuropsiquiatria i Addiccions, Hospital del Mar Barcelona, IMIM (Institut Hospital del Mar d'Investigacions Mediques), Universitat Autònoma de Barcelona, Barcelona, Spain.
Andrej KastelicNational Centre for the Treatment of Drug Addiction in Ljubljana, Ljubljana, Slovenia.
Stephan WalcherCONCEPT, Center for Addiction-Medicine, Munich, Germany.
Lorenzo SomainiAddiction Treatment Centre - Ser.D ASL BI - Local Health Unit, Biella, Italy.
Emily MulvihillKantar Health, New York, New York.
Jochen ErtlKantar Health, New York, New York.
Jason GrebelyThe Kirby Institute, UNSW Sydney, Sydney, Australia.ORCID 0000-0002-1833-2017
Kantar Health (United States) · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USNational Drug Addiction Center · BGOspedale degli Infermi · ITPrisma Health · USUniversitat Autònoma de Barcelona · ESUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this analysis was to evaluate perceived barriers related to HCV testing, management and treatment among physicians practicing in clinics offering opioid agonist treatment (OAT). C-SCOPE was a study consisting of a self-administered survey among physicians practicing at clinics providing OAT in Australia, Canada, Europe and the United States between April and May 2017. A 5-point Likert scale (1 = not a barrier, 3 = moderate barrier, 5 = extreme barrier) was used to measure responses to perceived barriers for HCV testing, evaluation and treatment across the domains of the health system, clinic and patient. Among the 203 physicians enrolled (40% USA, 45% Europe, 14% Australia/Canada), 21% were addiction medicine specialists, 29% psychiatrists and 69% were metro/urban. OAT physicians in this study reported poor access to on-site venepuncture (35%), point-of-care HCV testing (16%), and noninvasive liver disease assessment (25%). Only 30% of OAT physicians reported personally treating HCV infection. Major perceived health system barriers to HCV management included the lack of funding for noninvasive liver disease testing, long wait times to see an HCV specialist, lack of funding for new HCV therapies, and reimbursement restrictions based on drug/alcohol use. Major perceived clinic barriers included the lack of peer support programmes and/or HCV case managers to facilitate linkage to care, the need to refer people off-site for noninvasive liver disease staging, the lack of support for on-site phlebotomy and the lack of on-site delivery of HCV therapy. This study highlights several important modifiable barriers to enhance HCV testing, evaluation and treatment among PWID attending OAT clinics.

Indexed as

Disease ManagementAmbulatory Care FacilitiesAntiviral AgentsAustraliaCanadaCross-Sectional StudiesEuropeHepatitis CHumansInternationalityOpiate Substitution TreatmentPerceptionPhysiciansPoint-of-Care TestingPractice Patterns, Physicians'Substance Abuse, IntravenousAntiviral AgentsbarriersDAAhepatitis Copioid substitution therapyOSTpeople who inject drugstreatment

Identifiers

PMID31074167
PMCPMC6771477
OpenAlexW2943994554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.