ReviewOrthodontics & craniofacial research2019
Personalized scaffolding technologies for alveolar bone regenerative medicine.
Review in Orthodontics & craniofacial research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Use of cells and/or biologics combined with scaffolds in alveolar bone augmentation for implant site development.Journal of periodontology · 2026Pooled it
- Emerging, personalized, and minimally invasive technologies for periodontal and peri-implant soft and hard tissue regenerative therapy.Journal of periodontology · 2026Review
- The influence of soluble epoxide hydrolase inhibition and their PUFA-derived epoxides in osteoblast bone metabolism: an in vitro study.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2025Article
- Improved bone regeneration with bone targeted scaffold.Scientific reports · 2025Article
- In Vitro Biological Properties Assessment of 3D-Printed Hydroxyapatite-Polylactic Acid Scaffolds Intended for Bone Regeneration.Journal of functional biomaterials · 2025Article
- Additive manufacturing of patient-specific, biphasic implants with zonal design for regeneration of osteochondral defects-critical evaluation of the work flow from clinical MRI data to implantation.Materials today. Bio · 2025Article
- Challenges and Innovations in Alveolar Bone Regeneration: A Narrative Review on Materials, Techniques, Clinical Outcomes, and Future Directions.Medicina (Kaunas, Lithuania) · 2024Review
- Computational methods for biofabrication in tissue engineering and regenerative medicine - a literature review.Computational and structural biotechnology journal · 2024Review
- Recent Advances in Scaffolds for Guided Bone Regeneration.Biomimetics (Basel, Switzerland) · 2024Review
- Multidimensional 3D-Printed Scaffolds and Regeneration of Intrabony Periodontal Defects: A Systematic Review.Journal of functional biomaterials · 2024Review
- The Role of Cone Beam Computed Tomography in Periodontology: From 3D Models of Periodontal Defects to 3D-Printed Scaffolds.Journal of personalized medicine · 2024Article
- Towards Polycaprolactone-Based Scaffolds for Alveolar Bone Tissue Engineering: A Biomimetic Approach in a 3D Printing Technique.International journal of molecular sciences · 2023Review
- CBCT-Based Design of Patient-Specific 3D Bone Grafts for Periodontal Regeneration.Journal of clinical medicine · 2023Article
- Fabrication of Solvent-Free PCL/β-TCP Composite Fiber for 3D Printing: Physiochemical and Biological Investigation.Polymers · 2023Article
- A Review of Image-Based Simulation Applications in High-Value Manufacturing.Archives of computational methods in engineering : state of the art reviews · 2023Review
- Regenerative Medicine Technologies to Treat Dental, Oral, and Craniofacial Defects.Frontiers in bioengineering and biotechnology · 2021Review
- Current and future trends in periodontal tissue engineering and bone regeneration.Plastic and aesthetic research · 2021Article
- Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges.Journal of polymers and the environment · 2020Review
- Evaluation of the adhesion of human dental pulp stem cells to different endodontic biomaterials before and after setting.Journal of dental research, dental clinics, dental prospects · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
The reconstruction of alveolar bone defects associated with teeth and dental implants remains a clinical challenge in the treatment of patients affected by disease or injury of the alveolus. The aim of this review was to provide an overview on advances made in the use of personalized scaffolding technologies coupled with biologics, cells and gene therapies that offer future clinical applications for the treatment of patients requiring periodontal and alveolar bone regeneration. Over the past decade, advancements in three-dimensional (3D) imaging acquisition technologies such as cone-beam computed tomography (CBCT) and precise scaffold fabrication methods such as 3D bioprinting have resulted in personalized scaffolding constructs based on individual patient-specific anatomical data. Furthermore, 'fiber-guiding' scaffold designs utilize topographical cues to guide ligamentous fibers to form in orientation towards the root surface to improve tooth support. Therefore, a topic-focused literature search was conducted looking into fiber-guiding and image-based scaffolds and their associated clinical applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.