ArticleOrthodontics & craniofacial research2019
Mechanobiology of bone and suture - Results from a pig model.
Article in Orthodontics & craniofacial research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Unravelling the difference in craniofacial morphology of Yucatan miniature and standard pigs during postnatal ontogeny.Proceedings. Biological sciences · 2025Article
- Cyclic loading failed to promote growth in a pig model of midfacial hypoplasia.Journal of anatomy · 2024Article
- Article
- Three-dimensional morphometric analysis of cranial sutures - A novel approach to quantitative analysis.Bone reports · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo compare the morphology and mechanical function of sutures in normal pigs and minipigs to those of Yucatan minipigs, a natural model for midfacial hypoplasia. SETTING AND SAMPLE POPULATION: Research took place at the Department of Orthodontics at the University of Washington and used varying sample sizes of normal-snouted pigs and Yucatan minipigs. MATERIAL AND
methodsSkulls and heads were examined for morphology of the nasofrontal suture using computed tomography and histology. Strain gauge recordings were made of sutural strain during mastication and during cyclic tensile loading of the nasofrontal suture.
resultsSutures in Yucatans had narrower gaps than same-age normal pigs. The nasofrontal suture was simpler in construction and had more active osteoblasts on the bone fronts in Yucatans. The sutural ligament was less well organized, and based on a small sample, masticatory strain appeared to be lower than in normal minipigs. However, sutures were not fused and showed similar strains in response to the cyclic loading procedure.
conclusionMidfacial hypoplasia in Yucatan pigs has the likely proximate cause of hyperossification. Yet prior to fusion, the sutures appear to be amenable to treatment that would promote their growth rate.
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