ArticleJournal of neuro-oncology2019
Health-related quality of life of patients with brain metastases selected for stereotactic radiosurgery.
Article in Journal of neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- The long-term course and relationship with survival of multidimensional fatigue in patients with brain metastases after Gamma Knife radiosurgery.Journal of cancer research and clinical oncology · 2023Trial
- Living with brain metastases-A longitudinal qualitative study of patient experiences from time of diagnosis.Neuro-oncology practice · 2026Article
- Multiple brain metastases: resection with IORT versus adjuvant radiotherapy and concurrent irradiation of unresected lesions.Radiation oncology (London, England) · 2025Article
- Automated segmentation of brain metastases in T1-weighted contrast-enhanced MR images pre and post stereotactic radiosurgery.BMC medical imaging · 2025Article
- Quality of life after stereotactic radiosurgery for brain metastasis: an assessment from a prospective national registry.Journal of neuro-oncology · 2025Article
- BMScope: A scoping review to chart the evolving clinical study landscape in brain and leptomeningeal metastasis.Neuro-oncology · 2024Article
- Health-related quality of life after stereotactic radiosurgery in patients with brain metastases.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Outcome assessment of intraoperative radiotherapy for brain metastases: results of a prospective observational study with comparative matched-pair analysis.Journal of neuro-oncology · 2023Observational
- Quality of Life and Role of Palliative and Supportive Care for Patients With Brain Metastases and Caregivers: A Review.Frontiers in neurology · 2022Review
- Prophylactic cranial irradiation in non-small cell lung cancer: evidence and future development.Journal of thoracic disease · 2021Review
- Health-related quality of life after Gamma Knife radiosurgery in patients with 1-10 brain metastases.Journal of cancer research and clinical oncology · 2021Observational
- Cognitive functioning and predictors thereof in patients with 1-10 brain metastases selected for stereotactic radiosurgery.Journal of neuro-oncology · 2019Observational
- Multidimensional assessment of fatigue in patients with brain metastases before and after Gamma Knife radiosurgery.Journal of neuro-oncology · 2019Observational
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
purposeInformation on health-related quality of life (HRQoL) of patients with brain metastases (BM) before stereotactic radiosurgery (SRS) is very relevant to improve communication between patients and clinicians and to be able to interpret changes in HRQoL after SRS. The aim of this study was to evaluate the prevalence and severity of complaints on different aspects of pre-SRS HRQoL among patients with BM and to identify predictors thereof.
methodsPatients with 1-10 newly diagnosed BM, expected survival > 3 months, Karnofsky Performance Status ≥ 70, and scheduled to undergo SRS were included. HRQoL was measured with the Functional Assessment of Cancer Therapy-Brain (FACT-Br) questionnaire. One-sample z-tests were conducted to analyze differences between patients with BM and published normative data of a general adult sample and of an adult cancer sample. Multiple regression analyses were run to identify predictors of pre-SRS HRQoL.
resultsOn the individual level, most patients with BM (57.6% of 92 included patients) reported complaints regarding emotional well-being. As a group, patients with BM reported significantly lower emotional well-being compared to both control groups and significantly higher social well-being compared to the general population. Worse psychological factors, e.g. physical fatigue, depression, mental fatigue and anxiety, predicted aspects of pre-SRS HRQoL.
conclusionsAn increased understanding of pre-SRS HRQoL and predictors hereof, provides us with more insight into the well-being of our patients with BM and is necessary for the interpretation of (changes in) HRQoL after SRS.
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