ArticleIrish journal of medical science2019
Myasthenia gravis and pregnancy: retrospective evaluation of 27 pregnancies in a tertiary center and comparison with previous studies.
Article in Irish journal of medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Risk factors for pregnancy-related clinical outcome in myasthenia gravis: a systemic review and meta-analysis.Orphanet journal of rare diseases · 2022Pooled it
- Medication use trajectories in myasthenia gravis pregnancies: a population-based drug utilization study.Journal of neurology · 2026Article
- Characterizing Perinatal Treatment Patterns and Outcomes in Myasthenia Gravis.Muscle & nerve · 2026Article
- Is gastroesophageal reflux linked to inflammation-related gestational complications and poor obstetric history?BMC pregnancy and childbirth · 2026Article
- Challenges of a Pregnant Woman With Untreated Myasthenia Gravis: Delivery and Puerperium.Cureus · 2025Article
- Transient Neonatal Myasthenia Gravis as a Common Complication of a Rare Disease: A Systematic Review.Journal of clinical medicine · 2024Review
- Pregnancy outcomes for women with myasthenia gravis and their newborns: A nationwide register-based cohort study.European journal of neurology · 2024Article
- Myasthenia gravis and pregnancy: Lessons learned from a complex a case report.SAGE open medical case reports · 2024Article
- Choices and Challenges With Treatment of Myasthenia Gravis in Pregnancy: A Systematic Review.Cureus · 2023Review
- The burden of myasthenia gravis - highlighting the impact on family planning and the role of social support.Frontiers in neurology · 2023Article
- Myasthenia gravis in pregnancy: Systematic review and case series.Obstetric medicine · 2022Article
- Myasthenia Gravis Can Have Consequences for Pregnancy and the Developing Child.Frontiers in neurology · 2020Review
- Gender issues of antibody-mediated diseases in neurology: (NMOSD/autoimmune encephalitis/MG).Therapeutic advances in neurological disorders · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimTo share our experience with the management of pregnancies in women with myasthenia gravis (MG) in a tertiary center.
methodsThe study retrospectively evaluated 27 pregnancies in 12 patients. The pregnancies were divided into 3 groups on the basis of the clinical course of MG during pregnancy: improvement (n = 7), disease-stable (n = 9), and deterioration (n = 11). The groups were compared with respect to patient characteristics, clinical features, and obstetric outcomes.
resultsThere were 4 miscarriages (14.8%), 3 preterm births (11.1%), and 4 cases of preterm premature rupture of the membranes (PPROM) (14.8%). Exacerbation was observed in 25.9% of the cases; the remission rate during the postpartum period and after miscarriage was 37%. The cesarean section (CS) rate was 78.3%. Pregnancies with deterioration of MG were statistically more likely to have higher miscarriage, preterm birth, PPROM, CS, and transient neonatal MG rates, in addition to a lower gestational age at birth, birth weight, and 5-min Apgar score than pregnancies with improved or stable disease (p values < 0.001, 0.04, 0.03, 0.009, 0.02, < 0.001, 0.002, and 0.043, respectively).
conclusionPhysicians who manage pregnant women with MG must be familiar with the clinical features of the condition; a multidisciplinary approach is necessary for a better prognosis.
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