Evidence map›Paper›PMID 31073666›Full record

ReviewCurrent genetics2019

Centromeric non-coding RNA as a hidden epigenetic factor of the point centromere.

Yick Hin Ling, Karen Wing Yee Yuen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Centromeres Transcription and Transcripts for Better and for Worse.Progress in molecular and subcellular biology · 2021
    Article
  7. Review
  8. Epigenetic regulation of centromere function.Cellular and molecular life sciences : CMLS · 2020
    Review
  9. Review
  10. Review
  11. Genetics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yick Hin LingSchool of Biological Sciences, Kadoorie Biological Sciences Building, The University of Hong Kong, Pokfulam Road, Hong Kong, China.
Karen Wing Yee YuenSchool of Biological Sciences, Kadoorie Biological Sciences Building, The University of Hong Kong, Pokfulam Road, Hong Kong, China. kwyyuen@hku.hk.ORCID http://orcid.org/0000-0002-2139-5465
University of Hong Kong · HK

Funding

Hong Kong Research Grants Council General Research Fund 17113418the University of Hong Kong Seed Funds for Basic Research 201311159169the University of Hong Kong Seed Funds for Basic Research 201509159021
6 · The paper itself

Abstract

To ensure proper chromosome segregation during cell division, the centromere in many organisms is transcribed to produce a low level of long non-coding RNA to regulate the activity of the kinetochore. In the budding yeast point centromere, our recent work has shown that the level of centromeric RNAs (cenRNAs) is tightly regulated and repressed by the kinetochore protein Cbf1 and histone H2A variant H2A.Z

Indexed as

Epigenesis, GeneticCentromereChromosomal Proteins, Non-HistoneGene Expression RegulationGenomic InstabilityHistonesRNA, UntranslatedTranscription, GeneticChromosomal Proteins, Non-HistoneHistonesRNA, UntranslatedCentromere-binding factor Cbf1Centromeric histone variant CENP-ACentromeric transcriptionChromosome instabilityHistone H2A variant Htz1Long non-coding RNA

Identifiers

PMID31073666
OpenAlexW2944660651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.