ArticleJournal of pediatric intensive care2018
Medication Use as a Contributor to Fluid Overload in the PICU: A Prospective Observational Study.
Article in Journal of pediatric intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Association between early fluid overload and clinical outcomes in a pediatric ICU.Pediatric research · 2026Observational
- Association Between 25% Albumin and Fluid Balance in Mechanically Ventilated Children.Respiratory care · 2025Article
- Describing the determinants of fluid prescribing and fluid balance optimization in the pediatric intensive care unit: a qualitative study at a community hospital.Implementation science communications · 2025Article
- The determinants of fluid accumulation in critically ill children: a prospective single-center cohort study.Pediatric nephrology (Berlin, Germany) · 2025Article
- The Correlation of Fluid Creep with Fluid and Electrolyte Imbalance In Pediatric Intensive Care Unit Dr. Cipto Mangunkusumo National Central Public Hospital.Turkish archives of pediatrics · 2024Article
- Fluid volume used for medication delivery in critically ill adults.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Article
- Fluid therapy in mechanically ventilated critically ill children: the sodium, chloride and water burden of fluid creep.BMC pediatrics · 2020Article
- The path to great pediatric septic shock outcomes.Critical care (London, England) · 2018Article
- Fluid Overload in the PICU: Still a Challenge.Journal of pediatric intensive care · 2018Article
- A Standardized Approach to Reduce Fluid Overload in Critically Ill Children.Pediatric quality & safetyArticle
- Challenges in Pediatric Fluid Management: Insights into Nursing Practices and Knowledge.Sage open pediatricsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
In this prospective observational study, we explored the association of daily fluid intake from medication use with fluid overload in 75 children beginning 24 hours after intubation. The mean percent daily fluid intake from medications was 29% in the overall cohort. Excess intake and inadequate output contributed significantly to fluid overload. In the 28 patients who became ≥10% fluid overloaded, the mean percent daily fluid intake from medications was 34%, but just 23% in the patients who did not. Awareness of volume contribution and maximized concentration of parenteral medications when able may lessen the burden of fluid overload.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.