Evidence map›Paper›PMID 31073462›Full record

ArticleJournal of pediatric intensive care2018

Practice Recommendations for Early Mobilization in Critically Ill Children.

Karen Choong, Filomena Canci, Heather Clark, Ramona O Hopkins, Sapna R Kudchadkar, Jamil Lati, Brenda Morrow, Charmaine Neu, Beth Wieczorek, Carleen Zebuhr

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Journal of pediatric intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04989790 narecruitingnot on this mapstarted 2022, after this paper: background citation

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children: A Pragmatic, Stepped-wedge Trial

TypeinterventionalSponsorJohns Hopkins UniversityRan2022 to 2026Enrolled1,440ConditionsChild, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure UlcerArmsPICU Up!
NCT05296096 nacompletednot on this mapstarted 2023, after this paper: background citation

PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS - a Pilot Feasibility, Randomized Controlled Trial

TypeinterventionalSponsorBoston Children's HospitalRan2023 to 2026Enrolled18ConditionsMuscle Loss, Protein, Mobility, Pediatric ALLArmsProtein dosage and rehabilitation team delivered exercise prescription
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Early Protocolized Versus Usual Care Rehabilitation for Pediatric Neurocritical Care Patients: A Randomized Controlled Trial.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019
    Trial
  4. Review
  5. Article
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  8. Provision of physiotherapy services for children in intensive care units in Uganda: A descriptive study.The Southern African journal of critical care : the official journal of the Critical Care Society · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Article
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Karen ChoongDepartment of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
Filomena CanciPediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Heather ClarkPediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Ramona O HopkinsPsychology Department and Neuroscience Center, Brigham Young University, Provo, Utah, United States.
Sapna R KudchadkarDepartment of Anesthesiology and Critical Care Medicine and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Jamil LatiDivision of Rehabilitation, Department of Physical Therapy, University of Toronto, The Hospital for Sick Children, Toronto, Canada.
Brenda MorrowDepartment of Pediatrics and Child Health, University of Cape Town, South Africa.
Charmaine NeuPediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Beth WieczorekDepartment of Anesthesiology and Critical Care Medicine and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Carleen ZebuhrSection of Critical Care, Department of Pediatrics, Children's Hospital Colorado, Aurora, Colorado, United States.
McMaster Children's Hospital · CAJohns Hopkins University · USBrigham Young University · USChildren's Hospital Colorado · USImpact · CAUniversity of Cape Town · ZAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged immobility is associated with significant short- and long-term morbidities in critically ill adults and children. The majority of critically ill children remain immobilized while in the pediatric intensive care unit (PICU) due to limited awareness of associated morbidities, lack of comfort and knowledge on how to mobilize critically ill children, and the lack of pediatric-specific practice guidelines. The objective of this article was to develop consensus practice recommendations for safe, early mobilization (EM) in critically ill children. A group of 10 multidisciplinary experts with clinical and methodological expertise in physical rehabilitation, EM, and pediatric critical care collaborated to develop these recommendations. First, a systematic review was conducted to evaluate existing evidence on EM in children. Using an iterative process, the working document was circulated electronically to panel members until the group reached consensus. The group agreed that the overall goals of mobilization are to reduce PICU morbidities and optimize recovery. EM should therefore not be instituted in isolation but as part of a rehabilitation care bundle. Mobilization should not be delayed, but its appropriateness and safety should be assessed early. Increasing levels of physical activity should be individualized for each patient with the goal of achieving the highest level of functional mobility that is developmentally appropriate, for increasing durations, daily. We developed a system-based set of clinical safety criteria and a checklist to ensure the safety of mobilization in critically ill children. Although there is a paucity of pediatric evidence on the efficacy of EM, there is ample evidence that prolonged bed rest is harmful and should be avoided. These EM practice recommendations were developed to educate clinicians, encourage safe practices, reduce PICU-acquired morbidities, until future pediatric research provides evidence on effective rehabilitation interventions and how best to implement these in critically ill children.

Indexed as

critically ill childrenearly mobilizationphysiotherapypractice guidelines

Identifiers

PMID31073462
PMCPMC6260323
OpenAlexW2605671827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.