Evidence map›Paper›PMID 31073385›Full record

ArticleDementia & neuropsychologia

Association among 2-min step test, functional level and diagnosis of dementia.

Jessica Plácido, José Vinicius Ferreira, Felipe de Oliveira, Paula Sant'Anna, Renato Sobral Monteiro-Junior, Jerson Laks, Andrea C Deslandes

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jessica PlácidoBSc, Laboratory of Neuroscience of exercise (LANeX), Institute of Psychiatry, Federal University of Rio de Janeiro (UFRJ), RJ, Brazil.
José Vinicius FerreiraMSc, Laboratory of Neuroscience of exercise (LaNEx), Institute of Psychiatry, Federal University of Rio de Janeiro (UFRJ), RJ, Brazil.
Felipe de OliveiraBSc, Laboratory of Neuroscience of exercise (LaNEx), State University of Rio de Janeiro (UERJ), RJ, Brazil.
Paula Sant'AnnaBSc, Laboratory of Neuroscience of exercise (LaNEx), Institute of Psychiatry, Federal University of Rio de Janeiro (UFRJ), RJ, Brazil.
Renato Sobral Monteiro-JuniorPhD, Universidade Estadual de Montes Claros, Minas Gerais, Brazil.
Jerson LaksMD, PhD, Professor, Institute of Psychiatry, Federal University of Rio de Janeiro (UFRJ), RJ, Brazil.
Andrea C DeslandesPhD, Professor, Laboratory of Neuroscience of exercise (LaNEx), Institute of Psychiatry, Federal University of Rio de Janeiro (UFRJ), RJ, Brazil.
Universidade Federal do Rio de Janeiro · BRUniversidade do Estado do Rio de Janeiro · BRUniversidade Estadual de Montes Claros · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aerobic capacity declines significantly throughout life, beginning at the age of 30 years and accelerating from 60 years, where a decline of 17% per decade is expected thereafter.

objectiveTo investigate the association between aerobic capacity and a diagnosis of mild cognitive impairment (MCI), mild AD or moderate AD in older adults, considering the risk classification of functional loss of the Step test.

methodsIn this cross-sectional study, 93 patients (age >60 years) were evaluated (Healthy=36; MCI=18, AD=39). The step test was used to assess aerobic capacity, while overall cognitive status was measured using the MMSE. The groups were divided according to the risk classifications of functional loss into below or above the standard cut-off point for aerobic capacity.

resultsSubjects in the functional loss risk group were approximately ten to fourteen times more likely to be diagnosed with mild (OR:10.7; p=0.001) or moderate (OR.=14.7; p=0.002) AD than their fitter counterparts. Low aerobic fitness was also associated with the MCI condition (OR=4.5; p=0.05), but only after controlling for educational level, age and sex. In the overall sample (N=93), there was an association between aerobic capacity and MMSE performance (R

conclusionlow aerobic capacity was associated with cognitive decline, and older adults at risk of functional loss on the STEP test had greater chance of being diagnosed with MCI or AD after controlling for age, sex and education.

Indexed as

aerobic capacityAlzheimer’s diseasecognitive functionmild cognitive impairmentphysical function

Identifiers

PMID31073385
PMCPMC6497027
OpenAlexW2930681072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.