Evidence map›Paper›PMID 31073374›Full record

ArticleOncotarget2019

MicroRNA-203 impacts on the growth, aggressiveness and prognosis of hepatocellular carcinoma by targeting

Maria M Simile, Graziella Peitta, Maria L Tomasi, Stefania Brozzetti, Claudio F Feo, Alberto Porcu, Antonio Cigliano, Diego F Calvisi, Francesco Feo, Rosa M Pascale

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. RNA methyltransferase METTL16: Targets and function.Wiley interdisciplinary reviews. RNA · 2022
    Review
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  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Maria M SimileDepartment of Medical, Surgical and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, Sassari, Italy.
Graziella PeittaDepartment of Medical, Surgical and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, Sassari, Italy.
Maria L TomasiDepartment of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Stefania BrozzettiDepartment of Surgery "Pietro Valdoni", University of Rome "La Sapienza", Rome, Italy.
Claudio F FeoDepartment of Medical, Surgical and Experimental Sciences, Division of Surgery, University of Sassari, Sassari, Italy.
Alberto PorcuDepartment of Medical, Surgical and Experimental Sciences, Division of Surgery, University of Sassari, Sassari, Italy.
Antonio CiglianoInstitute of Pathology, University of Regensburg, Regensburg, Germany.
Diego F CalvisiDepartment of Medical, Surgical and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, Sassari, Italy.
Francesco FeoDepartment of Medical, Surgical and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, Sassari, Italy.
Rosa M PascaleDepartment of Medical, Surgical and Experimental Sciences, Division of Experimental Pathology and Oncology, University of Sassari, Sassari, Italy.
University of Sassari · ITCedars-Sinai Medical Center · USSapienza University of Rome · ITUniversity of Regensburg · DE

Funding

Role of Sumoylation in Alcoholic Liver DiseaseK01AA022372 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOMASI, MARIA LAUDA · 2013 to 2017
$803k
Role of SAMe on UBC9 and sumolyation in liver cancer and alcoholic liver injuryF32AA020150 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOMASI, MARIA LAUDA · 2010 to 2012
$154k
NIAAA NIH HHS F32 AA020150NIAAA NIH HHS K01 AA022372
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is characterized by the down-regulation of the liver-specific methyladenosyltransferase 1A (

Indexed as

HCC prognosisHCC therapymethionine metabolismmethyladenosyltransferasesS-adenosylmethionine

Identifiers

PMID31073374
PMCPMC6497462
OpenAlexW2944498485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.