Evidence map›Paper›PMID 31073332›Full record

ArticleBiotechnology for biofuels2019

Combining loss of function of

Hongli Xie, Nancy L Engle, Sivasankari Venketachalam, Chang Geun Yoo, Jaime Barros, Mitch Lecoultre, Nikki Howard, Guifen Li, Liang Sun, Avinash C Srivastava and 9 more

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. A group III patatin-like phospholipase geneFrontiers in plant science · 2023
    Article
  6. Article
  7. SorghumGenes · 2021
    Article
  8. Article
  9. SilencingFrontiers in plant science · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Hongli Xie1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Nancy L Engle2Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Sivasankari Venketachalam3Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602 USA.
Chang Geun Yoo2Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Jaime Barros4BioDiscovery Institute and Department of Biological Sciences, University of North Texas, Denton, TX 76203 USA.
Mitch Lecoultre1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Nikki Howard1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Guifen Li1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Liang Sun1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Avinash C Srivastava1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Sivakumar Pattathil3Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602 USA.
Yunqiao Pu2Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Michael G Hahn3Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602 USA.
Arthur J Ragauskas2Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Richard S Nelson1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Richard A Dixon4BioDiscovery Institute and Department of Biological Sciences, University of North Texas, Denton, TX 76203 USA.
Timothy J Tschaplinski2Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Elison B Blancaflor1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.
Yuhong Tang1Noble Research Institute, LLC, 2510 Sam Noble Parkway, Ardmore, OK 73401 USA.ORCID 0000-0003-2967-778X
United States Department of Energy · USOak Ridge National Laboratory · USNoble Research Institute · USUniversity of North Texas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDownregulation of genes involved in lignin biosynthesis and related biochemical pathways has been used as a strategy to improve biofuel production. Plant C1 metabolism provides the methyl units used for the methylation reactions carried out by two methyltransferases in the lignin biosynthetic pathway: caffeic acid 3-

resultsDouble

conclusionOur observations demonstrate that additional reduction in lignin content and improved sugar release can be achieved by simultaneous downregulation of a gene in the C1 (

Indexed as

caffeoyl-CoA 3-O-methyltransferase1ccoaomt1folylpolyglutamate synthetase1fpgs1Glycome profilingLigninMetabolite profilingPhenylpropanoid pathway

Identifiers

PMID31073332
PMCPMC6498598
OpenAlexW2943769323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.