Evidence map›Paper›PMID 31073295›Full record

ArticleFrontiers in neurology2019

Clinical Imaging Findings of Vestibular Aqueduct Trauma in a Patient With Posttraumatic Meniere's Syndrome.

David Bächinger, Madeline M Goosmann, Bernhard Schuknecht, Joseph B Nadol, Joe C Adams, Alexander Huber, Andreas H Eckhard

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

David BächingerDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland.
Madeline M GoosmannUniversity of Zurich, Zurich, Switzerland.
Bernhard SchuknechtMedical Radiological Institute MRI, Zurich, Switzerland.
Joseph B NadolDepartment of Otolaryngology, Harvard Medical School, Boston, MA, United States.
Joe C AdamsDepartment of Otolaryngology, Harvard Medical School, Boston, MA, United States.
Alexander HuberDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland.
Andreas H EckhardDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland.
University of Zurich · CHMassachusetts Eye and Ear Infirmary · USUniversity Hospital of Zurich · CH

Funding

NIDCD National Temporal Bone, Hearing and Balance Pathology Resource RegistryU24DC013983 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI LIBERMAN, M. CHARLES, QUESNEL, ALICIA M · 2014 to 2025
$6.5M
NIDCD NIH HHS U24 DC013983
6 · The paper itself

Abstract

Posttraumatic Meniere's syndrome is a rare clinical entity. The pathomechanism by which temporal bone trauma leads to fluctuating audiovestibular symptoms, in some cases with a delay of onset many years after trauma, remains elusive. Here, a clinical case and the respective temporal bone imaging data were reviewed to investigate the underlying inner ear pathology. A 44-year-old patient presented with left-sided Meniere's syndrome 34 years after he suffered an ipsilateral temporal bone fracture caused by a car accident. Clinical imaging showed left cochleovestibular hydrops (gadolinium-enhanced MRI) and bony obliteration of the left VA (CT imaging), resulting in discontinuity of the ES. Our findings suggest that a temporal bone fracture with a "retrolabyrinthine" course, traversing the VA, caused intraaqueductal callus bone formation and progressive blockage of the VA. As a result, the extraosseous (distal) endolymphatic sac (eES) became separated from the cochleovestibular labyrinth, an event that presumably underlies endolymphatic hydrops formation and that precipitates the onset of clinical Meniere's symptoms in this case.

Indexed as

endolymphatic hydropsendolymphatic sacgadolinium-enhanced magnetic resonance imagingotic capsuletemporal bone fracture

Identifiers

PMID31073295
PMCPMC6495004
OpenAlexW2941648403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.