Evidence map›Paper›PMID 31073275›Full record

ArticleMediators of inflammation2019

Anti-PD-1 Antibody Administration following Hip Fracture Surgery Reverses Immune Dysfunction and Decreases Susceptibility to Infection.

Hao Zhang, Chuying Chen, Jiusheng He, Jianzheng Zhang, Zhi Liu, Tiansheng Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hao ZhangDepartment of Orthopedic Surgery, Beijing Shunyi District Hospital, Shunyi District, Guangming South Street No. 3, Beijing 101300, China.ORCID 0000-0002-5573-9318
Chuying ChenDepartment of Orthopedic Surgery, Beijing Shunyi District Hospital, Shunyi District, Guangming South Street No. 3, Beijing 101300, China.
Jiusheng HeDepartment of Orthopedic Surgery, Beijing Shunyi District Hospital, Shunyi District, Guangming South Street No. 3, Beijing 101300, China.
Jianzheng ZhangDepartment of Orthopedic Surgery, The Seventh Medical Center of PLA, Dongcheng District, Nanmencang No. 5, Beijing 100700, China.
Zhi LiuDepartment of Orthopedic Surgery, The Seventh Medical Center of PLA, Dongcheng District, Nanmencang No. 5, Beijing 100700, China.
Tiansheng SunDepartment of Orthopedic Surgery, The Seventh Medical Center of PLA, Dongcheng District, Nanmencang No. 5, Beijing 100700, China.ORCID 0000-0002-4053-7297
Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this investigation was to assess expression of programmed death-1 (PD-1) and inflammatory status after hip fracture surgery in aged mice and to evaluate the effect of anti-PD-1 antibody intervention. Male C57BL/6 mice aged 22-28 months underwent hip fracture and femoral intramedullary pinning or a sham procedure. Expression of PD-1 was measured on CD4

Indexed as

AnimalsAntibodiesApoptosisCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCytokinesDisease Models, AnimalHip FracturesInflammationInterferon-gammaMaleMiceMice, Inbred C57BLProgrammed Cell Death 1 ReceptorAntibodiesCytokinesInterferon-gammaProgrammed Cell Death 1 Receptor

Identifiers

PMID31073275
PMCPMC6470458
OpenAlexW2925443509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.