Evidence map›Paper›PMID 31073189›Full record

Trial reportScientific reports2019

Symptom trajectories in patients with panic disorder in a primary care intervention: Results from a randomized controlled trial (PARADISE).

Karoline Lukaschek, Thomas S Hiller, Ulrike Schumacher, Tobias Teismann, Jörg Breitbart, Christian Brettschneider, Hans-Helmut König, Jürgen Margraf, Jochen Gensichen

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Karoline LukaschekInstitute of General Practice and Family Medicine, University Hospital of Ludwig-Maximilians-University Munich, Pettenkoferstr. 10, D-80336, Munich, Germany.
Thomas S HillerInstitute of General Practice and Family Medicine, Jena University Hospital, Bachstrasse 18, D-07743, Jena, Germany.
Ulrike SchumacherCentre for Clinical Studies, Jena University Hospital, Jena, Salvador-Allende-Platz 27, D-07747, Jena, Germany.
Tobias TeismannMental Health Research and Treatment Center, Ruhr-Universität Bochum, Massenbergstr. 11, D-44787, Bochum, Germany.
Jörg BreitbartInstitute of General Practice and Family Medicine, Jena University Hospital, Bachstrasse 18, D-07743, Jena, Germany.
Christian BrettschneiderDepartment of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-5280-1075
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246, Hamburg, Germany.
Jürgen MargrafMental Health Research and Treatment Center, Ruhr-Universität Bochum, Massenbergstr. 11, D-44787, Bochum, Germany.
Jochen GensichenInstitute of General Practice and Family Medicine, University Hospital of Ludwig-Maximilians-University Munich, Pettenkoferstr. 10, D-80336, Munich, Germany. jochen.gensichen@med.uni-muenchen.de.
Jena University Hospital · DERuhr University Bochum · DEUniversität Hamburg · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This analysis aims to identify and characterize symptom trajectories in primary care patients with panic disorder with/without agoraphobia (PD/AG) who participated in a primary care team based training involving elements of cognitive behavioural therapy (CBT). Growth Mixture Modeling was used to identify different latent classes of change in patients with PD/AG (N = 176) who underwent treatment including CBT elements. We identified three patient classes with distinct similar trajectories. Class 1 (n = 58, mean age: 46.2 years ± 13.4 years, 81% women) consisted of patients with an initially high symptom burden, but symptoms declined constantly over the intervention period. Symptoms of patients in class 2 (n = 89, mean age: 44.2 years ± 14.5 years, 67.4% women) declined rapidly at the beginning, then patients went into a plateau-phase. The third class (n = 29, mean age: 47.0 years ± 12.4 years, 65.5% women) was characterized by an unstable course and had the worse outcome. Our findings show that only a minority did not respond to the treatment. To identify this minority and refer to a specialist would help patients to get intensive care in time.

Indexed as

Cognitive Behavioral TherapyAdultAgoraphobiaEducational StatusFemaleHumansMaleMiddle AgedPanic DisorderPrimary Health CareTreatment Outcome

Identifiers

PMID31073189
PMCPMC6509250
OpenAlexW2944661576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.