Evidence map›Paper›PMID 31073068›Full record

ArticleHaematologica2020

A phase 1 trial of alisertib and romidepsin for relapsed/refractory aggressive B-cell and T-cell lymphomas.

Paolo Strati, Loretta J Nastoupil, Richard E Davis, Luis E Fayad, Nathan Fowler, Fredrick B Hagemeister, Larry Kwak, Yasuhiro Oki, Michael Wang, Jason Westin and 5 more

Abstract readClinical Trial, Phase ILetter
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Refractory Burkitt Lymphoma: Diagnosis and Interventional Strategies.Blood and lymphatic cancer : targets and therapy · 2024
    Review
  4. Review
  5. Article
  6. Targeting MYC-driven lymphoma: lessons learned and future directions.Cancer drug resistance (Alhambra, Calif.) · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Novel targeted therapies of T cell lymphomas.Journal of hematology & oncology · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Paolo StratiDivision of Cancer Medicine, MD Anderson Cancer Center, Houston, TX.
Loretta J NastoupilDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Richard E DavisDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Luis E FayadDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Nathan FowlerDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Fredrick B HagemeisterDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Larry KwakDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Yasuhiro OkiDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Michael WangDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Jason WestinDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Charnelle E RubenDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Emily T WessonDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Richard PiekarzInvestigational Drug Branch of CTEP, National Cancer Institute, Bethesda, MD, USA.
Michelle A FanaleDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.
Hun Ju LeeDepartment of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX hunlee@mdanderson.org.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DepsipeptidesLymphoma, T-CellLymphoma, T-Cell, PeripheralAzepinesB-LymphocytesHumansNeoplasm Recurrence, LocalPyrimidinesTreatment OutcomeAzepinesDepsipeptidesMLN 8237Pyrimidinesromidepsin

Identifiers

PMID31073068
PMCPMC6939506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.