ArticleScience (New York, N.Y.)2019
LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis.Epigenetics · 2023Pooled it
- Mammalian MemPrep establishes the lipid composition of ER membranes in HEK293T cells.EMBO reports · 2026Article
- The SLC-ome of membrane transport: from molecular discovery to physiology and clinical applications.Physiological reviews · 2026Review
- Expression, prognostic value and function of LMBR1L in gastric cancer.Molecular genetics and genomics : MGG · 2026Article
- Structural insights into predicted protein-protein interactions and protein complexes in the human proteome.Scientific reports · 2026Article
- Lipoic Acid-Intervened Decellularized Stem Cell Spheroid-Based Injectable Granular Gel for Diabetic Tissue Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- A Small-Molecule SLD1121 Activates Wnt/β-Catenin Signaling and Promotes Hair Growth via Targeting the Wnt Coreceptor LRP6.JACS Au · 2026Article
- The role of ER-associated degradation and ER-phagy in health and disease.Signal transduction and targeted therapy · 2026Review
- Pan-cancer analysis identifies LMBR1L as a prognostic and immunological biomarker with validation in colorectal cancer.European journal of medical research · 2025Article
- Evolutionary and structural bioinformatics identifies GPR89 as a conserved member of the LIMR protein superfamily.Computational and structural biotechnology journal · 2025Article
- Article
- lncRNA-WAL Promotes Triple-Negative Breast Cancer Aggression by Inducing β-Catenin Nuclear Translocation.Molecular cancer research : MCR · 2024Article
- The Dsc complex and its role in Golgi quality control.Biochemical Society transactions · 2024Review
- Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.EMBO reports · 2024Article
- Disruption of the ZFP574-THAP12 complex suppresses B cell malignancies in mice.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Viable mutations of mouse midnolin suppress B cell malignancies.The Journal of experimental medicine · 2024Article
- Identification of genetic suppressors for a BSCL2 lipodystrophy pathogenic variant in Caenorhabditis elegans.Disease models & mechanisms · 2024Article
- Effect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome.ACS omega · 2024Article
- Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 1 institution in 1 country.
Jin Huk Choi *Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0003-2483-4379
Xue Zhong *Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-6039-1793
William McAlpineCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-4611-5968
Tzu-Chieh LiaoCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-9992-8199
Duanwu ZhangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0003-2946-846X
Beibei FangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-0667-7421
Jamie RussellCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-9090-4067
Sara LudwigCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Evan Nair-GillCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-9876-7853
Zhao ZhangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-9345-3663
Kuan-Wen WangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Takuma MisawaCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Xiaoming ZhanCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0003-2045-5259
Mihwa ChoiCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Tao WangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Xiaohong LiCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0001-8357-5587
Miao TangCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-8708-3296
Qihua SunCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Liyang YuCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-7337-4420
Anne R MurrayCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-5586-635X
Eva Marie Y MorescoCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-2049-7291
Bruce BeutlerCenter for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. bruce.beutler@utsouthwestern.edu.ORCID 0000-0002-3639-246X
The University of Texas Southwestern Medical Center · US
Funding
Automated Forward Genetic Analysis of Adaptive ImmunityR01AI125581 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI BRUCE A BEUTLER · 2016 to 2026
$19.5MINTEGRATIVE IMMUNOLOGY TRAINING PROGRAMT32AI005284 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Nan Yan · 2003 to 2026
$7.4MThe Role of KBTBD2 in Lipodystrophy, Insulin Resistance, and DiabetesK99DK115766 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI ZHANG, ZHAO · 2017 to 2018
$182kNIAID NIH HHS R01 AI125581NIAID NIH HHS T32 AI005284NIDDK NIH HHS K99 DK115766
Abstract
Precise control of Wnt signaling is necessary for immune system development. In this study, we detected severely impaired development of all lymphoid lineages in mice, resulting from an
Indexed as
Wnt Signaling PathwayAnimalsbeta CateninHEK293 CellsHumansLymphopoiesisMice, Inbred C57BLMice, Mutant StrainsReceptors, Cell SurfaceWnt Proteinsbeta CateninLMBR1L protein, humanLmbr1l protein, mouseReceptors, Cell SurfaceWnt Proteins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.