Evidence map›Paper›PMID 31073030›Full record

ArticleThe Journal of biological chemistry2019

Activation of Tel1

Sarem Hailemariam, Sandeep Kumar, Peter M Burgers

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. DNA Damage and Replication Stress Checkpoints.Annual review of biochemistry · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Dynamic Properties of the DNA Damage Response Mre11/Rad50 Complex.International journal of molecular sciences · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM).Critical reviews in biochemistry and molecular biology · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Mechanism of auto-inhibition and activation of Mec1Nature structural & molecular biology · 2021
    Article
  18. Article
  19. Cryo-EM Structure of Nucleotide-Bound Tel1Structure (London, England : 1993) · 2020
    Article
  20. Structural basis of homologous recombination.Cellular and molecular life sciences : CMLS · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarem HailemariamFrom the Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110.
Sandeep KumarFrom the Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110.
Peter M BurgersFrom the Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110 burgers@wustl.edu.
Washington University in St. Louis · US

Funding

MECHANISMS OF DNA REPLICATION AND MAINTENANCE IN EUKARYOTESR35GM118129 · NIGMS · WASHINGTON UNIVERSITY · PI BURGERS, PETER M · 2016 to 2025
$6.7M
NIGMS NIH HHS R35 GM118129
6 · The paper itself

Abstract

In

Indexed as

NucleosomesDNA-Binding ProteinsDNA Breaks, Double-StrandedDNA, FungalEndodeoxyribonucleasesExodeoxyribonucleasesIntracellular Signaling Peptides and ProteinsProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNA-Binding ProteinsDNA, FungalEndodeoxyribonucleasesExodeoxyribonucleasesIntracellular Signaling Peptides and ProteinsMRE11 protein, S cerevisiaeNucleosomesProtein Serine-Threonine KinasesRAD50 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTEL1 protein, S cerevisiaeXRS2 protein, S cerevisiaeataxia telangiectasiaATMcheckpoint controlDNA damage responseMRNMRXphosphorylationPI3K

Identifiers

PMID31073030
PMCPMC6664182
OpenAlexW2944532305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.