Evidence map›Paper›PMID 31072917›Full record

SynthesisBioscience reports2019

Association of the TNF-α-308, TNF-α-238 gene polymorphisms with risk of bone-joint and spinal tuberculosis: a meta-analysis.

Wei Huang, Ruiyun Zhou, Jianfeng Li, Jianjun Wang, Hongwei Xiao

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei HuangDepartment of Spine and Osteology, Zhuhai People's Hospital, Zhuhai Hospital of Jinan University, Zhuhai, Guangdong Province 519000, China.
Ruiyun ZhouZhuhai Medical Emergency Center, Pre-Hospital Emergency Training Base Of Mid-southern China, Zhuhai, Guangdong Province 519000, China.
Jianfeng LiDepartment of Spine and Osteology, Zhuhai People's Hospital, Zhuhai Hospital of Jinan University, Zhuhai, Guangdong Province 519000, China.
Jianjun WangDepartment of Spine and Osteology, Zhuhai People's Hospital, Zhuhai Hospital of Jinan University, Zhuhai, Guangdong Province 519000, China.
Hongwei XiaoDepartment of Spine and Osteology, Zhuhai People's Hospital, Zhuhai Hospital of Jinan University, Zhuhai, Guangdong Province 519000, China jianfengli@yandex.com.ORCID 0000-0002-1859-2476

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to investigate the association of TNF-α-308 and TNF-α-238 gene polymorphisms with the risk of bone-joint and spinal tuberculosis (TB) by meta-analysis. By searching PubMed, Web of Science, Wanfang databases, CNKI, Medline, and Cochrane Library, the published articles about studies of the association of the TNF-α-308, TNF-α-238 gene polymorphisms with risk of bone-joint and spinal tuberculosis were collected by two reviewers. Begg's and Egger's tests were performed to assess publication bias. Stata 12.0 software was used for data analysis. The symmetry of the funnel plot indicated no significant publication bias in the Begg's test (A:

Indexed as

Genetic Predisposition to DiseaseModels, GeneticPolymorphism, Single NucleotidePromoter Regions, GeneticAllelesGenotypeHumansRisk FactorsTuberculosis, SpinalTumor Necrosis Factor-alphaTumor Necrosis Factor-alphaBone tuberculosisMeta-analysispolymorphismsTNF-α gene

Identifiers

PMID31072917
PMCPMC6542758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.