Evidence map›Paper›PMID 31072855›Full record

ArticleBMJ open2019

Assessing testing rates for viral hepatitis B and C by general practitioners in Flanders, Belgium: a registry-based study.

Rob Bielen, Özgür M Koc, Dana Busschots, Geert Robaeys, Bert Aertgeerts, Bert Vaes, Pavlos Mamouris, Catharina Mathei, Geert Goderis, Frederik Nevens

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rob BielenFaculty of Medicine and Life Sciences, Universiteit Hasselt, Hasselt, Belgium.ORCID 0000-0003-2258-2016
Özgür M KocFaculty of Medicine and Life Sciences, Universiteit Hasselt, Hasselt, Belgium.ORCID 0000-0003-3678-5703
Dana BusschotsFaculty of Medicine and Life Sciences, Universiteit Hasselt, Hasselt, Belgium.
Geert RobaeysFaculty of Medicine and Life Sciences, Universiteit Hasselt, Hasselt, Belgium.
Bert AertgeertsDepartment of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Bert VaesDepartment of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Pavlos MamourisDepartment of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Catharina MatheiDepartment of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Geert GoderisDepartment of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Frederik NevensDepartment of Gastroenterology and Hepatology, University Hospitals KULeuven, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesChronic infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) have a major impact on mortality worldwide. Although effective treatments are available for both HBV and HCV infection, <50% of the patients are even diagnosed in Belgium. This study assessed the real-life testing-and diagnosis rate by general practitioners (GPs) in Flanders, Belgium.

settingWe assessed the testing rate for HBV and HCV in 48 primary care practices with electronic medical records linked into one central registry in Flanders, Belgium.

participantsThe registry contains data of 440 140 patients over 20 years, which corresponds to 2.2% of the total Flemish population yearly. The primary care practices are distributed across Flanders and the patient population is representative for the distribution of age, gender and socioeconomic status at the community level.

resultsOf 440 140 patients included in the registry, 7892 (1.8%) patients were screened for hepatitis B surface antigen (HBsAg) and 7206 (1.6%) for hepatitis C antibody (HCV Ab) of whom 369 (4.7%) and 163 (2.3%) tested positive, respectively. Of 14 059 patients with chronic liver enzyme elevation, 1112 (7.9%) and 1395 (9.9%) were tested for HBsAg and HCV Ab, respectively. There was no improvement in testing rates over time.

conclusionsThis study demonstrates that real-life testing uptake for viral hepatitis B and C is suboptimal in the general practices in Flanders, even in patients with chronically elevated liver enzymes. As GPs play a crucial role in prevention, diagnosis and linkage to care, efforts and strategies to increase the testing uptake for HBV and HCV are urgently needed.

Indexed as

General PracticeAdultBelgiumFemaleHepatitis BHepatitis B Surface AntigensHepatitis CHepatitis C AntibodiesHumansLogistic ModelsMaleMiddle AgedRegistriesRisk FactorsSerologic TestsHepatitis B Surface AntigensHepatitis C Antibodiesgeneral practitionerstesting policyviral hepatitis

Identifiers

PMID31072855
PMCPMC6528017

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.