Evidence map›Paper›PMID 31072818›Full record

ArticleThe Journal of experimental medicine2019

Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses.

Mélanie Durand, Thomas Walter, Tiphène Pirnay, Thomas Naessens, Paul Gueguen, Christel Goudot, Sonia Lameiras, Qing Chang, Nafiseh Talaei, Olga Ornatsky and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 75 citations in OpenAlex.

  1. Macrophage heterogeneity in human secondary lymphoid organs.Clinical science (London, England : 1979) · 2026
    Review
  2. Review
  3. Review
  4. Multimodal analysis definesbioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
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  14. Article
  15. Article
  16. Review
  17. Review
  18. Naive and memory CD4iScience · 2022
    Article
  19. Single-cell analysis of myeloid cells in HPVFrontiers in immunology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Mélanie DurandInstitut Curie, Paris-Sciences-et-Lettres Research University, Institut National de la Santé et de la Recherche Médicale, U932, Paris, France.
Thomas WalterMines ParisTech, Paris-Sciences-et-Lettres Research University, Center for Computational Biology, Paris, France.
Tiphène PirnayInstitut Curie, Paris-Sciences-et-Lettres Research University, Institut National de la Santé et de la Recherche Médicale, U932, Paris, France.ORCID 0000-0002-1761-6835
Thomas NaessensTarget and Translational Science, Respiratory, Inflammation and Autoimmunity, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Gothenburg, Sweden.
Paul GueguenInstitut Curie, Paris-Sciences-et-Lettres Research University, Institut National de la Santé et de la Recherche Médicale, U932, Paris, France.ORCID 0000-0003-2930-6073
Christel GoudotInstitut Curie, Paris-Sciences-et-Lettres Research University, Institut National de la Santé et de la Recherche Médicale, U932, Paris, France.
Sonia LameirasInstitut Curie, Paris-Sciences-et-Lettres Research University, Next Generation Sequencing Platform, Paris, France.
Qing ChangFluidigm Canada Inc., Markham, Canada.
Nafiseh TalaeiFluidigm Canada Inc., Markham, Canada.
Olga OrnatskyFluidigm Canada Inc., Markham, Canada.
Tatiana VassilevskaiaFluidigm Canada Inc., Markham, Canada.
Sylvain BaulandeInstitut Curie, Paris-Sciences-et-Lettres Research University, Next Generation Sequencing Platform, Paris, France.ORCID 0000-0003-3104-1684
Sebastian AmigorenaInstitut Curie, Paris-Sciences-et-Lettres Research University, Institut National de la Santé et de la Recherche Médicale, U932, Paris, France.ORCID 0000-0001-8583-8416
Elodie SeguraInstitut Curie, Paris-Sciences-et-Lettres Research University, Institut National de la Santé et de la Recherche Médicale, U932, Paris, France elodie.segura@curie.fr.ORCID 0000-0003-1795-1921
Institut Curie · FRFluidigm (Canada) · CADélégation Paris 5 · FRAstraZeneca (Sweden) · SEÉcole Nationale Supérieure des Mines de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

Cell PolarityChemokine CXCL13Dendritic CellsHumansInterleukin-21InterleukinsLipopolysaccharide ReceptorsLymphoid TissueMacrophagesT-Lymphocytes, Helper-InducerT-Lymphocyte SubsetsChemokine CXCL13Interleukin-21InterleukinsLipopolysaccharide Receptors

Identifiers

PMID31072818
PMCPMC6605753
OpenAlexW2944510172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.