Evidence map›Paper›PMID 31072626›Full record

ReviewPsychosomatics

Psychological Considerations in Hematopoietic Stem Cell Transplantation.

Hermioni L Amonoo, Christina N Massey, Melanie E Freedman, Areej El-Jawahri, Halyna L Vitagliano, William F Pirl, Jeff C Huffman

Open access · greenAbstract readReview
In one paragraph

Review in Psychosomatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Effects of expressive helping writing during stem cell transplant: Randomized controlled trial.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Trial
  5. Article
  6. Article
  7. Patients' symptoms and challenges during the first year after allogeneic haematopoietic cell transplantation-patients' own expressions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Physical activity and sedentary behavior in patients during acute recovery from hematopoietic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Observational
  19. Article
  20. Predictive risk model of mild cognitive impairment in patients with malignant haematological diseases after haematopoietic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hermioni L AmonooDana Farber Cancer Institute, Department of Psychosocial Oncology, Brookline, MA; Brigham and Women's Hospital, Boston, MA; Department of Psychiatry, Harvard Medical School, Boston, MA. Electronic address: Hermioni_lokko@dfci.harard.edu.
Christina N MasseyMassachusetts General Hospital, Department of Psychiatry, Boston, MA.
Melanie E FreedmanMassachusetts General Hospital, Department of Psychiatry, Boston, MA.
Areej El-JawahriMassachusetts General Hospital, Department of Hematology/Oncology, Boston, MA.
Halyna L VitaglianoDana Farber Cancer Institute, Department of Psychosocial Oncology, Brookline, MA; Department of Psychiatry, Harvard Medical School, Boston, MA.
William F PirlDana Farber Cancer Institute, Department of Psychosocial Oncology, Brookline, MA; Department of Psychiatry, Harvard Medical School, Boston, MA.
Jeff C HuffmanDepartment of Psychiatry, Harvard Medical School, Boston, MA; Massachusetts General Hospital, Department of Psychiatry, Boston, MA.
Harvard University · USMassachusetts General Hospital · USDana-Farber Cancer Institute · US

Funding

Developing a positive psychology intervention to improve cardiac health behaviorsR01HL113272 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HUFFMAN, JEFF C · 2013 to 2017
$2.6M
A psychological-behavioral intervention for physical activity in type 2 diabetesR21DK109313 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HUFFMAN, JEFF C · 2016 to 2018
$470k
NHLBI NIH HHS R01 HL113272NIDDK NIH HHS R21 DK109313
6 · The paper itself

Abstract

backgroundIn recent decades, advances in transplantation medicine, and improved posttransplant care have reduced morbidity and mortality from hematopoietic stem cell transplantations (HSCTs). However, patients undergoing HSCT report a high prevalence of psychological distress, which can negatively impact recovery, function, and health outcomes, including mortality and higher risk of graft vs. host disease. Appropriate assessment and management of these psychological symptoms lead to better engagement with treatment and a variety of superior health outcomes.

objectiveWe provide a narrative review of the psychological challenges that accompany HSCT and suggest management approaches to equip psychiatric consultants involved in the care of this patient population.

methodsWe reviewed published work in PubMed, PsycInfo, and Scopus electronic databases on the common psychological challenges in HSCT, their vulnerability factors, as well as practical interventions for managing these challenges.

resultsWe outline the phases of the HSCT hospitalization and discuss common psychological challenges, such as depression, delirium, and post-traumatic stress reactions that accompany HSCT. We suggest an approach to psychiatric consults during the HSCT hospitalization and discuss practical interventions for managing psychological challenges in this population.

conclusionsThough pharmacological and behavioral interventions have been successfully used to treat psychosocial challenges in HSCT, further research is needed to understand the optimal psychiatric assessment tools, treatment strategies, and the long-term psychiatric care needed to address psychiatric comorbidities in this growing patient population.

Indexed as

DeliriumDepressionHematopoietic Stem Cell TransplantationHumansStress, PsychologicalAnxietyDeliriumDepressionHematopoietic stem cell transplantPosttraumatic stressPsychiatric consult

Identifiers

PMID31072626
PMCPMC6626677
OpenAlexW2911391382

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.