Evidence map›Paper›PMID 31072609›Full record

ReviewTrends in biotechnology2019

Wearable Devices for Single-Cell Sensing and Transfection.

Lingqian Chang, Yu-Chieh Wang, Faheem Ershad, Ruiguo Yang, Cunjiang Yu, Yubo Fan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Trends in biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Semi-Implantable Bioelectronics.Nano-micro letters · 2022
    Review
  5. Review
  6. Wearable Bioelectronics for Chronic Wound Management.Advanced functional materials · 2022
    Article
  7. Review
  8. Review
  9. Frontiers in chemistry · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lingqian ChangSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; Institute of Nanotechnology for Single Cell Analysis (INSCA), Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China; Department of Biomedical Engineering, University of North Texas, Denton, TX 76207, USA.
Yu-Chieh WangDepartment of Pharmaceutical Sciences, University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
Faheem ErshadDepartment of Biomedical Engineering, University of Houston, Houston, TX 77204, USA.
Ruiguo YangDepartment of Mechanical and Materials Engineering, University of Nebraska-Lincoln, NE 68588, USA; Center for Integrated Biomolecular Communications, University of Nebraska-Lincoln, Lincoln, NE 68588, USA. Electronic address: ryang6@unl.edu.
Cunjiang YuDepartment of Biomedical Engineering, University of Houston, Houston, TX 77204, USA; Department of Mechanical Engineering, Electrical and Computer Engineering, University of Houston, Houston, TX 77204, USA; Program of Materials Science and Engineering, University of Houston, Houston, TX 77204, USA. Electronic address: cyu13@centeral.uh.edu.
Yubo FanSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100083, China; Institute of Nanotechnology for Single Cell Analysis (INSCA), Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China. Electronic address: yubofan@buaa.edu.cn.

Funding

Targeted mass spectrometry approaches to understand CART processing and recepter interactionsP20GM113126 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI RAZAVI RIZI, MOHAMMAD · 2016 to 2025
$20.8M
Nebraska Center for Nanomedicine- Pilot ProjectsP30GM127200 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OUPICKY, DAVID · 2018 to 2022
$5.7M
Developing Hybrids of Cardiac Tissue and Biodegradable Electronics Towards Heart Implants with On-line Monitoring and Stimulating FunctionsR21EB026175 · NIBIB · UNIVERSITY OF HOUSTON · PI YU, CUNJIANG · 2018 to 2019
$468k
NIBIB NIH HHS R21 EB026175NIGMS NIH HHS P20 GM113126NIGMS NIH HHS P30 GM127200
6 · The paper itself

Abstract

Wearable healthcare devices are mainly used for biosensing and transdermal delivery. Recent advances in wearable biosensors allow for long-term and real-time monitoring of physiological conditions at a cellular resolution. Transdermal drug delivery systems have been further scaled down, enabling wide selections of cargo, from natural molecules (e.g., insulin and glucose) to bioengineered molecules (e.g., nanoparticles). Some emerging nanopatches show promise for precise single-cell gene transfection in vivo and have advantages over conventional tools in terms of delivery efficiency, safety, and controllability of delivered dose. In this review, we discuss recent technical advances in wearable micro/nano devices with unique capabilities or potential for single-cell biosensing and transfection in the skin or other organs, and suggest future directions for these fields.

Indexed as

AnimalsBiosensing TechniquesDrug Delivery SystemsHumansMonitoring, PhysiologicSkinTransfectionWearable Electronic Devicesbiosensorsdrug deliverygene transfectionsingle cellwearable electronics

Identifiers

PMID31072609
PMCPMC9245325

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.