Evidence map›Paper›PMID 31072578›Full record

ReviewJournal of the American College of Cardiology2019

Arrhythmia-Induced Cardiomyopathy: JACC State-of-the-Art Review.

Jose F Huizar, Kenneth A Ellenbogen, Alex Y Tan, Karoly Kaszala

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
176citing papers in PubMed, 4 pooled it
22.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

176 citing papers in PubMed, 4 syntheses or guidelines pooled it, 327 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Risk factors for the development of premature ventricular complex-induced cardiomyopathy: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Pooled it
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  5. Trial
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  9. Article
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  11. Prediabetes and the risk of atrial fibrillation and heart failure: a propensity-matched analysis in a real-world cohort.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  12. Article
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  14. Review
  15. Observational
  16. Article
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  18. Article
  19. Article
  20. Article

116 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jose F HuizarVirginia Commonwealth University/Pauley Heart Center, Richmond, Virginia; Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia. Electronic address: jfhuizar@gmail.com.
Kenneth A EllenbogenVirginia Commonwealth University/Pauley Heart Center, Richmond, Virginia.
Alex Y TanVirginia Commonwealth University/Pauley Heart Center, Richmond, Virginia; Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia.
Karoly KaszalaVirginia Commonwealth University/Pauley Heart Center, Richmond, Virginia; Hunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia.
Virginia Commonwealth University · US

Funding

Mechanistic Insights of Premature Ventricular Contractions-induced CardiomyopathyR01HL139874 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI HUIZAR, JOSE FRANCISCO · 2018 to 2020
$2.0M
Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS): A Pilot StudyR34HL138110 · NHLBI · RICHMOND INSTITUTE FOR VETERANS RESEARCH · PI DE MARCO, TERESA, ELLENBOGEN, KENNETH ALAN · 2017 to 2019
$601k
NHLBI NIH HHS R01 HL139874NHLBI NIH HHS R34 HL138110
6 · The paper itself

Abstract

Arrhythmias coexist in patients with heart failure (HF) and left ventricular (LV) dysfunction. Tachycardias, atrial fibrillation, and premature ventricular contractions are known to trigger a reversible dilated cardiomyopathy referred as arrhythmia-induced cardiomyopathy (AiCM). It remains unclear why some patients are more prone to develop AiCM despite similar arrhythmia burdens. The challenge is to determine whether arrhythmias are fully, partially, or at all responsible for an observed LV dysfunction. AiCM should be suspected in patients with mean heart rate >100 beats/min, atrial fibrillation, and/or premature ventricular contractions burden ≥10%. Reversal of cardiomyopathy by elimination of the arrhythmia confirms AiCM. Therapeutic choice depends on the culprit arrhythmia, patient comorbidities, and preferences. Following recovery of LV function, patients require continued follow-up if an abnormal myocardial substrate is present. Appropriate diagnosis and treatment of AiCM is likely to improve quality of life and clinical outcomes and to reduce hospital admission and health care spending.

Indexed as

Arrhythmias, CardiacCardiomyopathiesHumansPatient CareRecovery of FunctionVentricular Dysfunction, Leftarrhythmiacardiomyopathyheart failureleft ventricular dysfunctionpremature ventricular contractionssupraventricular tachycardia

Identifiers

PMID31072578
PMCPMC6538508
OpenAlexW2942876537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.