Evidence map›Paper›PMID 31072317›Full record

ArticleBMC psychiatry2019

Treating repetitive suicidal intrusions using eye movements: study protocol for a multicenter randomized clinical trial.

J S van Bentum, M Sijbrandij, A J F M Kerkhof, A Huisman, A R Arntz, E A Holmes, G Franx, J Mokkenstorm, M J H Huibers

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04181047 (RCT Investigating Virtual Eye Movement Desensitization and Reprocessing), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04181047 nacompletednot on this mapstarted 2021, after this paper: background citation

RCT Investigating Virtual Eye Movement Desensitization and Reprocessing (EMDR) for Adults With Suicidal Ideation

TypeinterventionalSponsorUniversity of AlbertaRan2021 to 2024Enrolled42ConditionsSuicidal IdeationArmsEye Movement Desensitization and Reprocessing (EMDR), Usual care
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

J S van BentumDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands. j.s.van.bentum@vu.nl.
M SijbrandijDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.
A J F M KerkhofDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.
A HuismanDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.
A R ArntzDepartment of Clinical Psychology, Universiteit van Amsterdam, Nieuwe Achtergracht 129, 1018 WS, Amsterdam, The Netherlands.
E A HolmesDepartment of Psychology, University of Uppsala, Campus Blåsenhus, Von Kraemers allé 1A och 1C, Uppsala, Sweden.
G FranxDepartment of Implementation, 113 Suicide Prevention, Paasheuvelweg 25, 1105 BP, Amsterdam, The Netherlands.
J MokkenstormDepartment of Psychiatry, Amsterdam Public Health Research Institute, Vrije Universiteit Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
M J H HuibersDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands.
Vrije Universiteit Amsterdam · NLGGD Amsterdam · NLGGZ inGeest · NLUniversity of Amsterdam · NLUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuicide is a major public health problem, and it remains unclear which processes link suicidal ideation and plans to the act of suicide. Growing evidence shows that the majority of suicidal patients diagnosed with major depression or bipolar disorder report repetitive suicide-related images and thoughts (suicidal intrusions). Various studies showed that vividness of negative as well as positive intrusive images may be reduced by dual task (e.g. eye movements) interventions taxing the working memory. We propose that a dual task intervention may also reduce frequency and intensity of suicidal imagery and may be crucial in preventing the transition from suicidal ideation and planning to actual suicidal behaviour. This study aims a) to evaluate the effectiveness of an Eye Movement Dual Task (EMDT) add-on intervention targeting suicidal imagery in depressed patients, b) to explore the role of potential moderators and mediators in explaining the effect of EMDT, and c) to evaluate the cost-effectiveness of EMDT.

methodsWe will conduct a multi-center randomized clinical trial (RCT) evaluating the effects of EMDT in combination with usual care (n = 45) compared to usual care alone (n = 45). Participants will fill in multiple online batteries of self-report questionnaires as well as complete a semi-structured interview (Intrusion Interview), and online computer tasks. The primary outcome is the frequency and intrusiveness of suicidal imagery. Furthermore, the vividness, emotionality, and content of the suicidal intrusions are evaluated; secondary outcomes include: suicidal behaviour and suicidal ideation, severity of depression, psychological symptoms, rumination, and hopelessness. Finally, potential moderators and mediators are assessed. DISCUSSION: If proven effective, EMDT can be added to regular treatment to reduce the frequency and vividness of suicidal imagery.

trial registrationThe study has been registered on October 17th, 2018 at the Netherlands Trial Register, part of the Dutch Cochrane Centre ( NTR7563 ).

Indexed as

Suicidal IdeationAdultCost-Benefit AnalysisDepressive DisorderEye Movement Desensitization ReprocessingEye MovementsFemaleHumansMaleMiddle AgedMulticenter Studies as TopicNetherlandsRandomized Controlled Trials as TopicSuicideSurveys and QuestionnairesTreatment OutcomeDual tasksEMDTMental imageryMulticenter randomized controlled trialSuicidal intrusionsSuicide

Identifiers

PMID31072317
PMCPMC6507069
OpenAlexW2944546192

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.